Next-generation sequencing (NGS) methods for cancer testing have been rapidly adopted
by clinical laboratories. To establish analytical validation best practice guidelines for NGS …

DNA sequencing continues to evolve quickly even after> 30 years. Many new platforms
suddenly appeared and former established systems have vanished in almost the same …

Nanopore DNA strand sequencing has emerged as a competitive, portable technology.
Reads exceeding 150 kilobases have been achieved, as have in-field detection and …

Objective Recent non-invasive prenatal testing (NIPT) technologies are based on next-
generation sequencing (NGS). NGS allows rapid and effective clinical diagnoses to be …

Massively parallel genome sequencing, also known as next-generation sequencing (NGS),
is the latest approach for preimplantation genetic diagnosis. The purpose of this study was to …

Abstract Background Though Illumina has largely dominated the RNA-Seq field, the
simultaneous availability of Ion Torrent has left scientists wondering which platform is most …

Increasing salinity levels in freshwater and coastal environments caused by sea level rise
linked to climate change is now recognized to be a major factor that can impact fish growth …

Use of next-generation sequencing to detect somatic variants in DNA extracted from formalin-
fixed, paraffin-embedded tumor tissues poses a challenge for clinical molecular diagnostic …

Real-time sequencing of short DNA reads has a wide variety of clinical and research
applications including screening for mutations, target sequences and aneuploidy. We …

MinION is a memory stick–sized nanopore-based sequencer designed primarily for single-
molecule sequencing of long DNA fragments (> 6 kb). We developed a library preparation …