SK Hanks, T Hunter - The FASEB journal, 1995 - Wiley Online Library
The eukaryotic protein kinases make up a large superfamily of homologous proteins. They are related by virtue of their kinase domains (also known as catalytic domains), which …
US DOE Joint Genome Institute: Hawkins Trevor 4 … - Nature, 2001 - nature.com
The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international …
C Widmann, S Gibson, MB Jarpe… - Physiological …, 1999 - journals.physiology.org
Widmann, Christian, Spencer Gibson, Matthew B. Jarpe, and Gary L. Johnson. Mitogen- Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human …
Protein phosphorylation plays a cardinal role in regulating many cellular processes in eukaryotes. In particular, protein phosphorylation is a major currency of signal transduction …
ENDOGENOUS neuromodulatory molecules are commonly coupled to specific metabolic enzymes to ensure rapid signal inactivation. Thus, acetylcholine is hydrolysed by …
S Keeney, CN Giroux, N Kleckner - Cell, 1997 - cell.com
Meiotic recombination in S. cerevisiae is initiated by double-strand breaks (DSBs). In certain mutants, breaks accumulate with a covalently attached protein, suggesting that cleavage is …
JE Sadler - Annual review of biochemistry, 1998 - annualreviews.org
Von Willebrand factor (VWF) is a blood glycoprotein that is required for normal hemostasis, and deficiency of VWF, or von Willebrand disease (VWD), is the most common inherited …
CM Fraser, JD Gocayne, O White, MD Adams… - Science, 1995 - science.org
The complete nucleotide sequence (580,070 base pairs) of the Mycoplasma genitalium genome, the smallest known genome of any free-living organism, has been determined by …
MS Wold - Annual review of biochemistry, 1997 - annualreviews.org
Replication protein A [RPA; also known as replication factor A (RFA) and human single- stranded DNA-binding protein] is a single-stranded DNA-binding protein that is required for …