The biological denitrification process is crucial for removing nitrogen and reducing nitrous
oxide (N2O) emissions. To investigate the mechanism of action of key enzymes in the …

Bioorthogonal catalysis (BC) generates chemical reactions not present in normal physiology
for the purpose of disease treatment. Because BC catalytically produces the desired therapy …

Regulating protein folding including assisting de novo folding, preventing misfolding and
aggregation, and facilitating refolding of proteins are of significant importance for retaining …

Disulfide‐bonded peptides and proteins, including hormones, toxins, growth factors, and
others, are abundant in living organisms. These molecules play crucial physiological roles …

Protein folding has become a tractable problem with the significant advances in deep
learning-driven protein structure prediction. Here we propose FoldPAthreader, a protein …

Thermostable exoshells (tES) are engineered proteinaceous nanoparticles used for the
rapid encapsulation of therapeutic proteins/enzymes, whereby the nanoplatform protects the …

Protein macromolecules occur naturally at the nanoscale. The use of a dedicated
nanoparticle as a lyophilization excipient, however, has not been reported. Because …

Alginate lyase can degrade alginate into oligosaccharides through β-elimination for various
biological, biorefinery, and agricultural purposes. Here, we report a novel PL7 family exolytic …

The protein folding problem has emerged as a new challenge with the significant advances
in deep learning driven protein structure prediction methods. While the structures of almost …

Protein refolding is a crucial procedure in bacterial recombinant expression. Aggregation
and misfolding are the two challenges that can affect the overall yield and specific activity of …