Impact of antibiotics on the human microbiome and consequences for host health

DV Patangia, C Anthony Ryan, E Dempsey… - …, 2022 - Wiley Online Library
It is well established that the gut microbiota plays an important role in host health and is
perturbed by several factors including antibiotics. Antibiotic‐induced changes in microbial …

Importance of inclusion of pregnant and breastfeeding women in COVID-19 therapeutic trials

S LaCourse, G John-Stewart… - Clinical Infectious …, 2020 - academic.oup.com
Investigators are employing unprecedented innovation in the design of clinical trials to
rapidly and rigorously assess potentially promising therapies for coronavirus disease 2019 …

[HTML][HTML] Sexually transmitted infections treatment guidelines, 2021

KA Workowski - MMWR. Recommendations and Reports, 2021 - cdc.gov
These guidelines for the treatment of persons who have or are at risk for sexually transmitted
infections (STIs) were updated by CDC after consultation with professionals knowledgeable …

[HTML][HTML] ISUOG Interim Guidance on coronavirus disease 2019 (COVID‐19) during pregnancy and puerperium: information for healthcare professionals–an update

LC Poon, H Yang, S Dumont, JCS Lee… - … in Obstetrics & …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), is a global public health emergency. Since the first …

Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study

H Fan, R Gilbert, F O'Callaghan, L Li - Bmj, 2020 - bmj.com
Objective To assess the association between macrolide antibiotics prescribing during
pregnancy and major malformations, cerebral palsy, epilepsy, attention deficit hyperactivity …

Environmental risk factors and congenital heart disease: an umbrella review of 165 systematic reviews and meta-analyses with more than 120 million participants

TN Zhang, QJ Wu, YS Liu, JL Lv, H Sun… - Frontiers in …, 2021 - frontiersin.org
Background: The etiology of congenital heart disease (CHD) has been extensively studied
in the past decades. Therefore, it is critical to clarify clear hierarchies of evidence between …

Assessment of evidence on reported non-genetic risk factors of congenital heart defects: The updated umbrella review

X Nie, X Liu, C Wang, Z Wu, Z Sun, J Su, R Yan… - BMC Pregnancy and …, 2022 - Springer
Background Congenital heart defect (CHD) is the leading cause of birth defects globally,
which results in a great disease burden. It is still imperative to detect the risk factors of CHD …

Antenatal, intrapartum and infant azithromycin to prevent stillbirths and infant deaths: study protocol for SANTE, a 2× 2 factorial randomised controlled trial in Mali

AJ Driscoll, FC Haidara, MD Tapia, EL Deichsel… - BMJ open, 2023 - bmjopen.bmj.com
Introduction In high mortality settings, prophylactic azithromycin has been shown to improve
birth weight and gestational age at birth when administered antenatally, to reduce the …

Use of azithromycin in pregnancy: More doubts than certainties

R Antonucci, L Cuzzolin, C Locci, F Dessole… - Clinical drug …, 2022 - Springer
Macrolides such as azithromycin are commonly prescribed antibiotics during pregnancy.
The good oral bioavailability and transplacental transfer of azithromycin make this drug …

Association between use of macrolides in pregnancy and risk of major birth defects: nationwide, register based cohort study

NW Andersson, RH Olsen, JT Andersen - bmj, 2021 - bmj.com
Objective To examine the association between the use of macrolide antibiotics in pregnancy
and the risk of major birth defects. Design Nationwide, register based cohort study. Setting …