The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

The successful clinical translation of platinum drugs for cancer treatment has witnessed an
upsurge in the development of metal compounds as therapeutics and diagnostics drugs …

With the rapid development of technology in the therapeutic field, metal-organic frameworks
(MOFs)/coordination polymers (CPs) can be considered as a progressive drug carrier for …

Late transition metal complexes that bear N-heterocyclic carbene (NHC) ligands have seen
a speedy growth in their use as both, metal-based drug candidates and potentially active …

N-Heterocyclic carbenes (NHCs) have been introduced as a new platform for the
development of anticancer metal complexes for several decades. NHCs as strong σ-donors …

Ruthenium (II) complexes developed for photodynamic therapy (PDT) are almost exclusively
tris-bidentate systems with C2 or D 3 symmetry. This is due to the fact that this structural …

Background: The inherent problems accompanying chemotherapy necessitate the
development of new anticancer approaches. The development of compounds that can …

Pincer complexes featuring tunable tridentate ligand frameworks are one of the most actively
studied classes of metal-based complexes. Currently, growing attention is devoted to the …

Colon and breast cancers were two of the four major cancers by age and sex group in
America for 2016 [1]. The number of deaths from colon cancer is higher than that from breast …

The most significant recent developments in the chemistry of transition metal complexes with
poly-N-heterocyclic carbene ligands (poly-NHCs) are reviewed herein. In particular …