Mitochondrial sirtuins in reproduction

G Di Emidio, S Falone, PG Artini, F Amicarelli… - Antioxidants, 2021 - mdpi.com
Mitochondria act as hubs of numerous metabolic pathways. Mitochondrial dysfunctions
contribute to altering the redox balance and predispose to aging and metabolic alterations …

Two strongly linked single nucleotide polymorphisms (Q320P and V397I) in GDF9 gene are associated with litter size in cashmere goats

X Wang, Q Yang, K Wang, H Yan, C Pan, H Chen, J Liu… - Theriogenology, 2019 - Elsevier
Abstract Growth differentiation factor 9 (GDF9) gene is an effective intra-ovarian regulator; it
plays a crucial role in early folliculogenesis in female mammals. The non synonymous …

Comprehensive analysis of mRNAs and miRNAs in the ovarian follicles of uniparous and multiple goats at estrus phase

X Zou, T Lu, Z Zhao, G Liu, Z Lian, Y Guo, B Sun, D Liu… - BMC genomics, 2020 - Springer
Background Fertility is an important economic trait in the production of meat goat, and
follicular development plays an important role in fertility. Although many mRNAs and …

Effect of Upregulation of Transcription Factor TFDP1 Binding Promoter Activity Due to RBP4 g.36491960G>C Mutation on the Proliferation of Goat Granulosa Cells

Y Liu, S Guo, X He, Y Jiang, Q Hong, R Lan, M Chu - Cells, 2022 - mdpi.com
Retinol-binding protein 4 (RBP4), a member of the lipocalin family, is a specific carrier of
retinol (vitamin A) in the blood. Numerous studies have shown that RBP4 plays an important …

A novel missense mutation (L280V) within POU1F1 gene strongly affects litter size and growth traits in goat

Y Zhang, W Cui, H Yang, M Wang, H Yan, H Zhu, J Liu… - Theriogenology, 2019 - Elsevier
In mammals, POU1F1 is a key transcription factor that directly affects the secretion of
pituitary hormones (GH, PRL, and TSH) and maintains growth and development. The aim of …

Whole genome re-sequencing reveals artificial and natural selection for milk traits in East Friesian sheep

X Li, L Yuan, W Wang, D Zhang, Y Zhao… - Frontiers in Veterinary …, 2022 - frontiersin.org
The East Friesian sheep is one of the important high-yielding dairy sheep breeds, but still
little is known about their genetic and genomic variation during domestication. Therefore, we …

Correlation analysis of candidate gene SNP for high-yield in Liaoning cashmere goats with litter size and cashmere performance

C Yue, WL Bai, YY Zheng, TY Hui, JM Sun… - Animal …, 2021 - Taylor & Francis
This study was designed to identify the relationship of four genes (GDF9, BMPR-IB, FecB
and ESR) polymorphisms in the 3′ UTR region with litter size and cashmere performance …

Genome-wide selection signatures analysis of litter size in Dazu black goats using single-nucleotide polymorphism

XH Duan, JH Zhang, YF Huang, YJ Zhao, RS Na… - 3 Biotech, 2019 - Springer
Litter size is considered to be the most important index for estimating domestic animal
productivity. The number of indigenous goats in China with higher litter sizes than those of …

A 20-bp insertion/deletion (indel) polymorphism within the CDC25A gene and its associations with growth traits in goat

W Cui, N Liu, X Zhang, Y Zhang, L Qu… - Archives Animal …, 2019 - aab.copernicus.org
Cell division cycle 25A (CDC25A), a member of the CDC25 family of phosphatases, is
required for progression from G1 to the S phase of the cell cycle. CDC25A provides an …

[HTML][HTML] Potential Candidate Genes Associated with Litter Size in Goats: A Review

W Chen, Y Han, Y Chen, X Liu, H Liang… - Animals: an Open …, 2025 - pmc.ncbi.nlm.nih.gov
This review examines genetic markers associated with litter size in goats, a key reproductive
trait impacting productivity in small ruminant farming. Goats play a vital socioeconomic role …