Helices are the most prevalent secondary structure in biomolecules and play vital roles in
their activity. Chemists have been fascinated with mimicking this molecular conformation …

Recent developments in the modification of methionine and other thioether-containing
residues in peptides, polypeptides, and proteins are reviewed. Properties and potential …

Sulfonium‐ion‐containing polymers exhibit significant potential benefits for various
applications. An efficient strategy to synthesize a type of antibacterial sulfonium‐ion‐bearing …

Antimicrobial peptides (AMPs) exhibit mighty antibacterial properties without inducing drug
resistance. Achieving much higher selectivity of AMPs towards bacteria and normal cells has …

Introduction: One of the major limiting steps in order to have an effective drug is the passage
through one or more cell membranes to reach its site of action. To reach the action-site, the …

Glycosylation is one of the most prevalent post-translational modifications of a protein, with a
defining impact on its structure and function. Many of the proteins involved in the innate or …

Controlling the topology of polymer-modified proteins has attracted growing interest.
However, one of the main challenges in this field is the lack of efficient and site-specific …

Here we report a brand-new bioactive polymer featuring sulfonium moieties that exhibits the
capability of inducing immunogenic cell death (ICD) for anticancer therapy. The optimized …

Abstract antibiotic resistance and drug-resistant bacterial infections pose significant threats
to public health. Antimicrobial peptides (AMPs) are a promising candidate for related …

Methionine is one of the most hydrophobic, redox-sensitive, and one of the only two sulfur-
containing amino acids on protein. Because of these biochemical properties, the methionine …