The prevalence of type‐2 diabetes (T2D) is increasing significantly throughout the globe since the last decade. This heterogeneous and multifactorial disease, also known as insulin …
Y Lee, K Jeon, JT Lee, S Kim, VN Kim - The EMBO journal, 2002 - embopress.org
MicroRNAs (miRNAs) constitute a novel, phylogenetically extensive family of small RNAs (∼ 22 nucleotides) with potential roles in gene regulation. Apart from the finding that miRNAs …
MicroRNAs (miRNAs) are short RNAs that post-transcriptionally regulate the expression of target genes by binding to the target mRNAs. Although a large number of animal miRNAs …
In the elucidation of the microRNA regulatory network, knowledge of potential targets is of highest importance. Among existing target prediction methods, RNAhybrid [M. Rehmsmeier …
NJ Park, H Zhou, D Elashoff, BS Henson… - Clinical Cancer …, 2009 - AACR
Purpose: We have previously shown that a transcriptome is found in saliva and subpanels of these mRNAs can be used as oral cancer biomarkers. In this study, we measured the …
C Llave, KD Kasschau, MA Rector… - The Plant Cell, 2002 - academic.oup.com
A large set of endogenous small RNAs of predominantly 21 to 24 nucleotides was identified in Arabidopsis. These small RNAs resembled micro-RNAs from animals and were similar in …
JY Yu, SL DeRuiter, DL Turner - Proceedings of the …, 2002 - National Acad Sciences
Duplexes of 21-nt RNAs, known as short-interfering RNAs (siRNAs), efficiently inhibit gene expression by RNA interference (RNAi) when introduced into mammalian cells. We show …
Y Karube, H Tanaka, H Osada, S Tomida… - Cancer …, 2005 - Wiley Online Library
Emerging evidence suggests that microRNA, which are well‐conserved, abundant and small regulatory RNA, may be involved in the pathogenesis of human cancers. We recently …
Noncoding RNAs (ncRNAs) have been found to have roles in a great variety of processes, including transcriptional regulation, chromosome replication, RNA processing and …