Natural products and analogues are a source of antibacterial drug discovery. Considering
drug resistance levels emerging for antibiotics, identification of bacterial metalloenzymes …

The pharmacokinetics profile of active pharmaceutical ingredients (APIs) in the solid
pharmaceutical dosage forms is largely dependent on the solid-state characteristics of the …

In recent years, nanocrystal technology has been extensively investigated. Due to the
submicron particle size and unique physicochemical properties of nanocrystals, they …

During the development of a pharmaceutical formulation, a powerful tool is needed to extract
the key points from the complicated process parameters and material attributes. Artificial …

In vitro dissolution that predicts the in vivo performance of solid preparations is extremely
important in formulation optimization. Fraction absorbed (F a) has been used to screen in …

Personalized medicine strives to deliver the 'right drug at the right dose'by considering inter-
person variability, one of the causes for therapeutic failure in specialized populations of …

Lipid-based formulations (LBFs) have demonstrated a great potential in enhancing the oral
absorption of poorly water-soluble drugs. However, construction of in vitro and in vivo …

In vitro–in vivo correlation (IVIVC) allows prediction of the in vivo performance of a
pharmaceutical product based on its in vitro drug release profiles and can be used to …

The primary focus of this review is a discussion regarding in vitro media for colon release,
but we also give a brief overview of colon delivery and the colon microbiota as a baseline for …

The use of controlled drug delivery systems represents an alternative and promising strategy
for the use of antimicrobials in the oral cavity. Microparticles, films and oral tablets based on …