Low temperature additive manufacturing of three dimensional scaffolds for bone-tissue engineering applications: Processing related challenges and property …

A Kumar, S Mandal, S Barui, R Vasireddi… - Materials Science and …, 2016 - Elsevier
In the last two decades, additive manufacturing (AM) has made significant progress towards
the fabrication of biomaterials and tissue engineering constructs. One direction of research …

Magnesium alloys as degradable biomaterials

Y Zheng - 2015 - books.google.com
This book provides a comprehensive review of the biomedical applications of biodegradable
magnesium and its alloys. It discusses the basic concepts of biodegradation mechanisms as …

A bioactive hydrogel and 3D printed polycaprolactone system for bone tissue engineering

I Hernandez, A Kumar, B Joddar - Gels, 2017 - mdpi.com
In this study, a hybrid system consisting of 3D printed polycaprolactone (PCL) filled with
hydrogel was developed as an application for reconstruction of long bone defects, which are …

Osteoblast cellular activity on low elastic modulus Ti–24Nb–4Zr–8Sn alloy

KC Nune, RDK Misra, SJ Li, YL Hao, R Yang - Dental materials, 2017 - Elsevier
Objectives Low modulus β-titanium alloys with non-toxic alloying elements are envisaged to
provide good biocompatibility and alleviate the undesired stress shielding effect. The …

Hydroxyapatite‐titanium bulk composites for bone tissue engineering applications

A Kumar, K Biswas, B Basu - Journal of Biomedical Materials …, 2015 - Wiley Online Library
The research work on bulk hydroxyapatite (HA)‐based composites are driven by the need to
develop biomaterials with better mechanical properties without compromising its bioactivity …

Surface nanotopography-induced favorable modulation of bioactivity and osteoconductive potential of anodized 3D printed Ti-6Al-4V alloy mesh structure

KC Nune, RDK Misra, X Gai, SJ Li… - Journal of biomaterials …, 2018 - journals.sagepub.com
The objective of the study described here is to fundamentally elucidate the biological
response of 3D printed Ti-6Al-4V alloy mesh structures that were surface modified to …

On the toughness enhancement in hydroxyapatite-based composites

A Kumar, K Biswas, B Basu - Acta Materialia, 2013 - Elsevier
Among various biologically compatible materials, hydroxyapatite (HA) has excellent
bioactivity/osteointegration properties and therefore has been extensively investigated for …

C ellular response of osteoblasts to low modulus Ti‐24Nb‐4Zr‐8Sn alloy mesh structure

KC Nune, RDK Misra, SJ Li, YL Hao… - Journal of Biomedical …, 2017 - Wiley Online Library
Abstract Titanium alloys (Ti‐6Al‐4V and Ti‐6Al‐7Nb) are widely used for implants, which are
characterized by high elastic modulus (∼ 110 GPa) with (α+ β) structure and that may …

The correlation between osseointegration and bonding strength at the bone-implant interface: In-vivo & ex-vivo investigations on hydroxyapatite and hydroxyapatite …

F Ghadami, MA Hamedani, G Rouhi… - Journal of …, 2022 - Elsevier
This study investigated the effects of hydroxyapatite (HA) and hydroxyapatite/titanium (HA/Ti)
coatings on osseointegration and bonding strength at the bone-implant interface. The …

Design and biological functionality of a novel hybrid Ti‐6 A l‐4 V/hydrogel system for reconstruction of bone defects

A Kumar, KC Nune, RDK Misra - Journal of tissue engineering …, 2018 - Wiley Online Library
We have designed a unique injectable bioactive hydrogel comprising of alginate, gelatin,
and nanocrystalline hydroxyapatite and loaded with osteoblasts, with the ability to infiltrate …