Research Progress on the Construction and Application of a Diabetic Zebrafish Model

Y Cao, Q Chen, Y Liu, L Jin, R Peng - International Journal of Molecular …, 2023 - mdpi.com
Diabetes is a metabolic disease characterized by high blood glucose levels. With economic
development and lifestyle changes, the prevalence of diabetes is increasing yearly. Thus, it …

Neurodegeneration, neuroprotection and regeneration in the zebrafish retina

SL Stella Jr, JS Geathers, SR Weber, MA Grillo… - Cells, 2021 - mdpi.com
Neurodegenerative retinal diseases, such as glaucoma and diabetic retinopathy, involve a
gradual loss of neurons in the retina as the disease progresses. Central nervous system …

Chitosan-based nanogels: synthesis and toxicity profile for drug delivery to articular joints

S Manivong, A Garcia Ac, SA Patten, JC Fernandes… - Nanomaterials, 2022 - mdpi.com
One important challenge in treating avascular-degraded cartilage is the development of new
drugs for both pain management and joint preservation. Considerable efforts have been …

Cyclophosphamide affects eye development and locomotion in zebrafish (Danio rerio)

D Li, W Sun, H Chen, H Lei, X Li, H Liu, G Huang… - Science of The Total …, 2022 - Elsevier
Cyclophosphamide (CP) is a broad-spectrum anticancer drug and has been frequently
detected in aquatic environments due to its incomplete removal by wastewater treatment …

[HTML][HTML] Therapeutic investigation of quercetin nanomedicine in a zebrafish model of diabetic retinopathy

S Wang, S Du, W Wang, F Zhang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetic retinopathy (DR) is progressive damage to the retina and it's caused by damage to
the blood-retinal barrier. Quercetin has pleiotropic action like anti-oxidant, regulation cell …

Activation of Retinal Angiogenesis in Hyperglycemic pdx1−/− Zebrafish Mutants

LM Wiggenhauser, H Qi, SJ Stoll, L Metzger… - Diabetes, 2020 - Am Diabetes Assoc
Progression from the initial vascular response upon hyperglycemia to a proliferative stage
with neovacularizations is the hallmark of proliferative diabetic retinopathy. Here, we report …

Which Hyperglycemic Model of Zebrafish (Danio rerio) Suites My Type 2 Diabetes Mellitus Research? A Scoring System for Available Methods

A Salehpour, M Rezaei, A Khoradmehr… - Frontiers in cell and …, 2021 - frontiersin.org
Despite extensive studies on type 2 diabetes mellitus (T2DM), there is no definitive cure,
drug, or prevention. Therefore, for developing new therapeutics, proper study models of …

[HTML][HTML] 儿童远视储备影响因素研究进展

赵梦雅, 朱懿, 许韶君, 陶芳标 - 中华流行病学杂志, 2022 - html.rhhz.net
近年来, 我国儿童青少年的近视问题呈现普遍化, 低龄化, 重度化趋势, 近视发生前的远视储备
受到越来越多的关注. 远视储备过早消耗是近视快速和过早发生的预测因素 …

Vitamin D regulates insulin pathway and glucose metabolism in zebrafish (Danio rerio)

R Shao, X Liao, Y Lan, H Zhang, L Jiao… - The FASEB …, 2022 - Wiley Online Library
dihydroxyvitamin D3 [1, 25 (OH) 2D3], the most active vitamin D (VD) metabolite, is a steroid
hormone playing an important role in many physiological functions in addition to maintaining …

An overview towards zebrafish larvae as a model for ocular diseases

JGS Rosa, M Lopes-Ferreira, C Lima - International Journal of Molecular …, 2023 - mdpi.com
Despite the obvious morphological differences in the visual system, zebrafish share a similar
architecture and components of the same embryonic origin as humans. The zebrafish retina …