Objective Childhood irritability, operationalized as disproportionate and frequent temper
tantrums and low frustration tolerance relative to peers, is a transdiagnostic symptom across …

Among youths, pathological irritability is highly prevalent and severely disabling. As a
frequent symptom, it often leads to referrals to child and adolescent mental health services …

Objective The need to understand and treat childhood chronic irritability (CI; ie frequent
temper loss and angry/irritable mood) is imperative. CI predicts impairment across …

Background Irritability is a transdiagnostic psychiatric phenotype defined as an increased
proneness to anger relative to peers. Trauma is defined as actual or threatened death …

Objective Aberrant responses to frustration are central mechanisms of pediatric irritability,
which is a common reason for psychiatric consultation and a risk factor for affective disorders …

Background Self‐regulation in early childhood develops within a social context. Variations in
such development can be attributed to inter‐individual behavioral differences, which can be …

Obsessive-compulsive disorder (OCD) is phenomenologically heterogeneous. While
predominant models suggest fear and harm prevention drive compulsions, many patients …

Elevated youth irritability is characterized by increased proneness to frustration relative to
peers when rewards are blocked, and is a transdiagnostic symptom that predicts multiple …

Background Irritability is a common symptom that may affect children's brain development.
This study aims to (1) characterize age-dependent and age-independent neural correlates …

The association between cognitive flexibility and related neural functioning has been
inconsistent. This is particularly true in young children, where previous studies have found …