Sex differences in offspring risk and resilience following 11β-hydroxylase antagonism in a rodent model of maternal immune activation

J Martz, MA Shelton, L Geist, ML Seney… - …, 2024 - nature.com
Maternal immune activation (MIA) puts offspring at greater risk for neurodevelopmental
disorders associated with impaired social behavior. While it is known that immune signaling …

Decoding the language of fear: Unveiling objective and subjective indicators in rodent models through a systematic review and meta-analysis

L Bao, J Rao, D Yu, B Zheng, B Yin - Neuroscience & Biobehavioral …, 2024 - Elsevier
While rodent models are vital for studying mental disorders, the underestimation of construct
validity of fear indicators has led to limitations in translating to effective clinical treatments …

Male rats emit aversive 44-kHz ultrasonic vocalizations during prolonged Pavlovian fear conditioning

KH Olszyński, R Polowy, AD Wardak, IA Łaska… - eLife, 2024 - elifesciences.org
Rats are believed to communicate their emotional state by emitting two distinct types of
ultrasonic vocalizations. The first is long '22-kHz'vocalizations (> 300 ms,< 32-kHz) with …

Examining brain activity responses during rat ultrasonic vocalization playback: Insights from a novel fMRI translational paradigm

LE Granata, A Chang, H Shaheed, A Shinde… - eneuro, 2024 - eneuro.org
Despite decades of preclinical investigation, there remains limited understanding of the
etiology and biological underpinnings of anxiety disorders. Sensitivity to potential threat is …

[HTML][HTML] 22 and 50 kHz rat ultrasonic vocalization playback reveals sex differences in behavior and cFos in brain regions associated with affective processing

SM Bonauto, KA Patel, JA Honeycutt - Behavioural Brain Research, 2025 - Elsevier
Adult rats communicate using ultrasonic vocalization (USV) frequencies indicating negative
(22 kHz) or positive (50 kHz) affective states. Playback of USVs can serve as an …

Affectively Valenced 22 and 55 Khz Rat Ultrasonic Vocalization Playback Reveals Sex Differences in Behavior and Cfos in Brain Regions Associated with Affective …

SM Bonauto, KA Patel, JA Honeycutt - Available at SSRN 4936429 - papers.ssrn.com
Adult rats communicate using ultrasonic vocalizations (USVs) frequencies indicating
negative (22 kHz) or positive (50-55 kHz) affective states. Playback of USVs can serve as an …