Expansion microscopy of apicomplexan parasites

B Liffner, S Absalon - Molecular Microbiology, 2024 - Wiley Online Library
Apicomplexan parasites comprise significant pathogens of humans, livestock and wildlife,
but also represent a diverse group of eukaryotes with interesting and unique cell biology …

Protocols for Plasmodium gametocyte production in vitro: an integrative review and analysis

R Omorou, I Bin Sa'id, M Delves, C Severini… - Parasites & …, 2022 - Springer
Abstract Background The production of Plasmodium gametocytes in vitro is a real challenge.
Many protocols have been described, but few have resulted in the production of viable and …

Novel systems to study vector-pathogen interactions in malaria

M Parres-Mercader, A Pance… - Frontiers in Cellular and …, 2023 - frontiersin.org
Some parasitic diseases, such as malaria, require two hosts to complete their lifecycle: a
human and an insect vector. Although most malaria research has focused on parasite …

The molecular mechanisms driving Plasmodium cell division

DS Guttery, M Zeeshan, AA Holder… - Biochemical Society …, 2024 - portlandpress.com
Malaria, a vector borne disease, is a major global health and socioeconomic problem
caused by the apicomplexan protozoan parasite Plasmodium. The parasite alternates …

PbARID-associated chromatin remodeling events are essential for gametocyte development in Plasmodium

T Nishi, I Kaneko, S Iwanaga, M Yuda - Nucleic Acids Research, 2024 - academic.oup.com
Gametocyte development of the Plasmodium parasite is a key step for transmission of the
parasite. Male and female gametocytes are produced from a subpopulation of asexual blood …

Unbiased phage display screening identifies hidden malaria vaccine targets

M Jacobs-Lorena, SJ Cha - Emerging Microbes & Infections, 2024 - Taylor & Francis
Malaria is among the deadliest infectious diseases. Over 200 million annual clinical malaria
cases are reported and more than half a million people, mostly children, die every year. The …

Nanobodies against Pfs230 block Plasmodium falciparum transmission

MH Dietrich, M Gabriela, K Reaksudsan… - Biochemical …, 2022 - portlandpress.com
Transmission blocking interventions can stop malaria parasite transmission from mosquito to
human by inhibiting parasite infection in mosquitos. One of the most advanced candidates …

Ready for Renascence in Mosquito: The Regulation of Gene Expression in Plasmodium Sexual Development

C Liu, J Tang, K Liang, P Liu, Z Li - Acta Tropica, 2024 - Elsevier
Malaria remains one of the most perilous vector-borne infectious diseases for humans
globally. Sexual gametocyte represents the exclusive stage at which malaria parasites are …

Phenotypic Screens Identify Genetic Factors Associated with Gametocyte Development in the Human Malaria Parasite Plasmodium falciparum

J Chawla, I Goldowitz, J Oberstaller… - Microbiology …, 2023 - Am Soc Microbiol
Transmission of the deadly malaria parasite Plasmodium falciparum from humans to
mosquitoes is achieved by specialized intraerythrocytic sexual forms called gametocytes …

Mosquito Salivary Antigens and Their Relationship to Dengue and P. vivax Malaria

MKM Howell, OM Olajiga, JC Cardenas… - Pathogens, 2024 - mdpi.com
In tropical areas, the simultaneous transmission of multiple vector-borne diseases is
common due to ecological factors shared by arthropod vectors. Malaria and dengue virus …