RE Denroche, L Mullen, L Timms, T Beck, CK Yung… - BMC Research …, 2015 - Springer
Background Accurate detection of somatic single nucleotide variants and small insertions and deletions from DNA sequencing experiments of tumour-normal pairs is a challenging …
DZ Derryberry, MC Cowperthwaite, CO Wilke - PeerJ, 2016 - peerj.com
We examined 55 technical sequencing replicates of Glioblastoma multiforme (GBM) tumors from The Cancer Genome Atlas (TCGA) to ascertain the degree of repeatability in calling …
Cancer, which affects hundreds of thousands of people worldwide every year and costs billions in treatment, is a disease caused by mutations that arise in somatic cell lines and …