Cortical layer 6b is considered by many to be a remnant of the subplate that forms during
early stages of neocortical development, but its role in the adult is not well understood. Its …

Abstract Three-dimensional (3D) reconstruction of living brain tissue down to an individual
synapse level would create opportunities for decoding the dynamics and structure–function …

Neuroinflammation has been reported to be associated with white matter injury (WMI) after
subarachnoid hemorrhage (SAH). As the main resident immune cells of the brain, microglia …

Mapping the complex and dense arrangement of cells and their connectivity in brain tissue
demands nanoscale spatial resolution imaging. Super-resolution optical microscopy excels …

The deepest layer of the cortex (layer 6b [L6b]) contains relatively few neurons, but it is the
only cortical layer responsive to the potent wake-promoting neuropeptide orexin/hypocretin …

The subregions of the entorhinal cortex (EC) are conventionally thought to compute
dichotomous representations for spatial processing, with the medial EC (MEC) providing a …

Episodic memory, which refers to our ability to encode and recall past events, is essential to
our daily lives. Previous research has established that both the entorhinal cortex (EC) and …

The ability to care for the young is innate and readily displayed by postpartum females after
delivery to ensure offspring survival. Upon pup exposure, rodent virgin (nulliparous) females …

Visual information is important for accurate spatial coding and memory-guided navigation.
As a crucial area for spatial cognition, the medial entorhinal cortex (MEC) harbors diverse …

This review article gives an overview on the molecular, cellular and network mechanisms
underlying focal seizures in neocortical networks with developmental malformations …