Bones are metabolically active organs. Their reconstruction is crucial for the proper
functioning of the skeletal system during bone growth and remodeling, fracture healing, and …

Annually, millions of patients suffer from irreversible injury owing to the loss or failure of an
organ or tissue caused by accident, aging, or disease. The combination of injectable …

The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …

An understanding of the structural complexity of mineralised tissues is fundamental for
exploration into the field of diagenesis. Here we review aspects of current and past research …

Over the course of a century, the meaning of interoception has changed from the restrictive
to the inclusive. In its inclusive sense, it bears relevance to every individual via its link to …

This review describes the role of bone cells and their surrounding matrix in maintaining
bone strength through the process of bone remodeling. Subsequently, this work focusses on …

Bone tissue engineering involves biomaterials, cells and regulatory factors to make
biosynthetic bone grafts with efficient mineralization for regeneration of fractured or …

Disruption of bone remodelling by diseases such as osteoporosis results in an imbalance
between bone formation by osteoblasts and resorption by osteoclasts. Research into these …

Injuries of bone and cartilage constitute important health issues costing the National Health
Service billions of pounds annually, in the UK only. Moreover, these damages can become …

Patients with CKD have a 4–fivefold higher rate of fractures. The incidence of fractures
increases with deterioration of kidney function. The process of skeletal changes in CKD …