Emerging diversity in lipid–protein interactions
Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …
membrane environment for proteins to being embedded in to detailed roles in complicated …
Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …
composition and structure, functional over a wide range of time scales, and characterized by …
Membrane proteins bind lipids selectively to modulate their structure and function
Previous studies have established that the folding, structure and function of membrane
proteins are influenced by their lipid environments,,,,,, and that lipids can bind to specific …
proteins are influenced by their lipid environments,,,,,, and that lipids can bind to specific …
MemProtMD: automated insertion of membrane protein structures into explicit lipid membranes
There has been exponential growth in the number of membrane protein structures
determined. Nevertheless, these structures are usually resolved in the absence of their lipid …
determined. Nevertheless, these structures are usually resolved in the absence of their lipid …
Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1
T Althoff, DJ Mills, JL Popot, W Kühlbrandt - The EMBO journal, 2011 - embopress.org
The respiratory chain in the inner mitochondrial membrane contains three large multi‐
enzyme complexes that together establish the proton gradient for ATP synthesis, and …
enzyme complexes that together establish the proton gradient for ATP synthesis, and …
Patchwork organization of the yeast plasma membrane into numerous coexisting domains
F Spira, NS Mueller, G Beck, P Von Olshausen… - Nature cell …, 2012 - nature.com
The plasma membrane is made up of lipids and proteins, and serves as an active interface
between the cell and its environment. Many plasma-membrane proteins are laterally …
between the cell and its environment. Many plasma-membrane proteins are laterally …
Highly permeable artificial water channels that can self-assemble into two-dimensional arrays
Bioinspired artificial water channels aim to combine the high permeability and selectivity of
biological aquaporin (AQP) water channels with chemical stability. Here, we carefully …
biological aquaporin (AQP) water channels with chemical stability. Here, we carefully …
From coarse grained to atomistic: a serial multiscale approach to membrane protein simulations
PJ Stansfeld, MSP Sansom - Journal of chemical theory and …, 2011 - ACS Publications
Coarse-grained molecular dynamics provides a means for simulating the assembly and the
interactions of membrane protein/lipid complexes at a reduced level of representation …
interactions of membrane protein/lipid complexes at a reduced level of representation …
Specificity of intramembrane protein–lipid interactions
FX Contreras, AM Ernst… - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
Our concept of biological membranes has markedly changed, from the fluid mosaic model to
the current model that lipids and proteins have the ability to separate into microdomains …
the current model that lipids and proteins have the ability to separate into microdomains …
GROmaρs: A GROMACS-based toolset to analyze density maps derived from molecular dynamics simulations
We introduce a computational toolset, named GROmaρs, to obtain and compare time-
averaged density maps from molecular dynamics simulations. GROmaρs efficiently …
averaged density maps from molecular dynamics simulations. GROmaρs efficiently …