Huntington disease (HD), a devastating autosomal-dominant neurodegenerative disease
caused by an expanded CAG trinucleotide repeat, is clinically characterized by a triad of …

The gut-brain axis is an essential communication pathway between the central nervous
system (CNS) and the gastrointestinal tract. The human microbiota is composed of a diverse …

In Huntington's disease (HD), a key pathological feature includes the development of
inclusion-bodies of fragments of the mutant huntingtin protein in the neurons of the striatum …

As Huntington's disease (HD) progresses, there is a significant loss of neurons in the
striatum in addition to a distinct thinning of the cerebral cortex. Despite an early presence of …

Introduction The hippocampus and striatum have dissociable roles in memory and are
necessary for spatial and procedural/cued learning, respectively. Emotionally charged …

Tubulin-associated unit (Tau) is a microtubule-associated protein, whose abnormal
phosphorylation and deposition in the brain characterizes a range of neurodegenerative …

Настоящий обзор посвящен рассмотрению патологических внутриклеточных
механизмов, характерных для болезни Хантингтона (Гентингтона) и центральной роли …