Background: Bisphosphonates are drugs commonly used for the medication and prevention
of diseases caused by decreased mineral density. Despite such important medicinal use …

Osteosarcoma or osteogenic sarcoma is the most common and prevalent cancerous tumor
of bone and occurs especially in children and teens. Recent treatment strategy includes a …

Objectives Diabetes mellitus (DM), cancer and cardiovascular diseases (CVD) are major
contributors to human miseries and death. Additionally, previous findings stated that cancer …

Background Most primary and metastatic bone tumors demonstrate increased osteoclast
activity and bone resorption. Current treatment is based on a combination of surgery …

Lung cancer is one of the most widely recognised types of cancer and the acquisition of
resistance towards chemotherapeutic drugs worsens the situation. Therefore, a site-directed …

Bone and bone-related diseases are the major cause of mobility hindrance and mortality in
humans and there is no effective and safe treatment for most of them, especially, for bone …

In recent years, many bacteria have developed resistance to commonly used antibiotics. It is
well-known that calcium is essential for bacterial function and cell wall stability …

The aim of this study was to develop and validate a rapid and sensitive reverse-phase high
performance liquid chromatography method for the quantitative determination of zoledronic …

Osteosarcoma (OS) is amongst the most commonly diagnosed bone tumors occurring in
adolescence, young adults and adults over the age of 65. Current treatment is based on a …

Bisphosphonates (BPs) are a group of organophosphorus compounds which are used in the
treatment of various bone related diseases. BPs possess a high affinity to the calcium in …