Molecular mechanisms of ischaemia-reperfusion injury and regeneration in the liver-shock and surgery-associated changes

E Pretzsch, H Nieß, NB Khaled, F Bösch… - International Journal of …, 2022 - mdpi.com
Hepatic ischemia-reperfusion injury (IRI) represents a major challenge during liver surgery,
liver preservation for transplantation, and can cause hemorrhagic shock with severe …

[HTML][HTML] Non-coding RNAs: The potential biomarker or therapeutic target in hepatic ischemia-reperfusion injury

JL Shao, LJ Wang, J Xiao, JF Yang - World Journal of …, 2023 - ncbi.nlm.nih.gov
Hepatic ischemia-reperfusion injury (HIRI) is the major complication of liver surgery and liver
transplantation, that may increase the postoperative morbidity, mortality, tumor progression …

Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo

Y Zhang, W Zhao, Y Chen, H Yuan, H Fang… - Nature …, 2021 - nature.com
Reversible NIR luminescent probes with negligible photocytotoxicity are required for long-
term tracking of cycling hypoxia in vivo. However, almost all of the reported organic …

MicroRNA-302a-3p induces ferroptosis of non-small cell lung cancer cells via targeting ferroportin

D Wei, YQ Ke, P Duan, L Zhou, CY Wang… - Free radical …, 2021 - Taylor & Francis
Ferroptosis is a newly described regulated form of cell death that contributes to the
progression of non-small cell lung cancers (NSCLCs). MicroRNA-302a-3p (miR-302a-3p) …

[HTML][HTML] MiR-191 inhibit angiogenesis after acute ischemic stroke targeting VEZF1

K Du, C Zhao, L Wang, Y Wang, KZ Zhang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Acute ischemic stroke (AIS) is a major public health problem in China. Impaired
angiogenesis plays crucial roles in the development of ischemic cerebral injury. Recent …

A novel microRNA-based prognostic model outperforms standard prognostic models in patients with acetaminophen-induced acute liver failure

OD Tavabie, CJ Karvellas, S Salehi, JL Speiser… - Journal of …, 2021 - Elsevier
Background & Aims Acetaminophen (APAP)-induced acute liver failure (ALF) remains the
most common cause of ALF in the Western world. Conventional prognostic models, utilising …

Overexpression of lncRNA HULC attenuates myocardial ischemia/reperfusion injury in rat models and apoptosis of hypoxia/reoxygenation cardiomyocytes via …

H Liang, F Li, H Li, R Wang, M Du - Immunological Investigations, 2021 - Taylor & Francis
Objective Acute myocardial infarction (AMI) is characterized by myocardial tissue necrosis
and activation of inflammatory response. This study aims to elucidate the potential …

[HTML][HTML] The deubiquitinase OTUD1 stabilizes NRF2 to alleviate hepatic ischemia/reperfusion injury

Q Zhang, Z Chen, J Li, K Huang, Z Ding, B Chen, T Ren… - Redox Biology, 2024 - Elsevier
Hepatic ischemia/reperfusion (I/R) injury is an important cause of liver function impairment
following liver surgery. The ubiquitin-proteasome system (UPS) plays a crucial role in …

Sevoflurane postconditioning attenuates hepatic ischemia-reperfusion injury by limiting HMGB1/TLR4/NF-κB pathway via modulating microRNA-142 in vivo and in …

L Xu, F Ge, Y Hu, Y Yu, K Guo, C Miao - Frontiers in Pharmacology, 2021 - frontiersin.org
Preconditioning of sevoflurane (Sevo) has been demonstrated to protect the liver from
ischemia/reperfusion (I/R) injury. However, it is unknown whether it has hepatoprotective …

Mesenchymal Stem Cells Derived Extracellular Vesicles Alleviate Traumatic Hemorrhagic Shock Induced Hepatic Injury via IL-10/PTPN22-Mediated M2 Kupffer Cell …

Y Zhang, X Zhang, H Zhang, P Song, W Pan… - Frontiers in …, 2022 - frontiersin.org
Traumatic hemorrhagic shock (THS) is a major cause of mortality and morbidity worldwide in
severely injured patients. Mesenchymal stem cells (MSCs) possess immunomodulatory …