Structural basis for the functional properties of the P2X7 receptor for extracellular ATP
The P2X7 receptor, originally known as the P2Z receptor due to its distinctive functional
properties, has a structure characteristic of the ATP-gated ion channel P2X receptor family …
properties, has a structure characteristic of the ATP-gated ion channel P2X receptor family …
The P2X7 receptor in mood disorders: Emerging target in immunopsychiatry, from bench to bedside
IA von Mücke-Heim, JM Deussing - Neuropharmacology, 2023 - Elsevier
Psychiatric disorders are among the most burdensome disorders worldwide. Though
therapies have evolved over the last decades, treatment resistance still affects many …
therapies have evolved over the last decades, treatment resistance still affects many …
P2X7R mediates the synergistic effect of ATP and MSU crystals to induce acute gouty arthritis
X Li, A Wan, Y Liu, M Li, Z Zhu, C Luo… - Oxidative medicine and …, 2023 - Wiley Online Library
Activation of the nod‐like receptor protein 3 (NLRP3) inflammasome by monosodium urate
(MSU) crystals has been identified as the molecular basis for the acute inflammatory …
(MSU) crystals has been identified as the molecular basis for the acute inflammatory …
Tyrosine 288 in the extracellular domain of the human P2X7 receptor is critical for receptor function revealed by structural modeling and site‐directed mutagenesis
EA Caseley, SP Muench… - … : Structure, Function, and …, 2022 - Wiley Online Library
Abstract The P2X7 receptor (P2X7R) is a calcium‐permeable cation channel activated by
high concentrations of extracellular ATP. It plays a role in vital physiological processes …
high concentrations of extracellular ATP. It plays a role in vital physiological processes …
[PDF][PDF] Research Article P2X7R Mediates the Synergistic Effect of ATP and MSU Crystals to Induce Acute Gouty Arthritis
X Li, A Wan, Y Liu, M Li, Z Zhu, C Luo, J Tao - 2023 - pdfs.semanticscholar.org
Activation of the nod-like receptor protein 3 (NLRP3) inflammasome by monosodium urate
(MSU) crystals has been identified as the molecular basis for the acute inflammatory …
(MSU) crystals has been identified as the molecular basis for the acute inflammatory …