Atlas-based finite element analyses with simpler constitutive models predict personalized progression of knee osteoarthritis: data from the osteoarthritis initiative

ME Mononen, A Paz, MK Liukkonen, MJ Turunen - Scientific Reports, 2023 - nature.com
New technologies are required to support a radical shift towards preventive healthcare. Here
we focus on evaluating the possibility of finite element (FE) analysis-aided prevention of …

Towards a transferable modeling method of the knee to distinguish between future healthy joints from osteoarthritic joints: data from the osteoarthritis initiative

A Paz, JJ García, RK Korhonen… - Annals of Biomedical …, 2023 - Springer
Computational models can be used to predict the onset and progression of knee
osteoarthritis. Ensuring the transferability of these approaches among computational …

Visible and near-infrared spectroscopy enables differentiation of normal and early osteoarthritic human knee joint articular cartilage

A Linus, P Tanska, JK Sarin, E Nippolainen… - Annals of Biomedical …, 2023 - Springer
Osteoarthritis degenerates cartilage and impairs joint function. Early intervention
opportunities are missed as current diagnostic methods are insensitive to early tissue …

Two-stage Classification of future knee osteoarthritis severity after 8 Years using MRI: data from the osteoarthritis initiative

TAT Nurmirinta, MJ Turunen, RK Korhonen… - Annals of Biomedical …, 2024 - Springer
Currently, there are no methods or tools available in clinical practice for classifying future
knee osteoarthritis (KOA). In this study, we aimed to fill this gap by classifying future KOA into …

Use of patellofemoral digital twins for patellar tracking and treatment prediction: Comparison of 3D models and contact detection algorithms

F Michaud, A Luaces, F Mouzo… - … in Bioengineering and …, 2024 - frontiersin.org
Introduction: Poor patellar tracking can result in painful contact pressures, patella
subluxation, or dislocation. The use of musculoskeletal models and simulations in …

Robust automatic hexahedral cartilage meshing framework enables population-based computational studies of the knee

KD Gibbons, V Malbouby, O Alvarez… - … in Bioengineering and …, 2022 - frontiersin.org
Osteoarthritis of the knee is increasingly prevalent as our population ages, representing an
increasing financial burden, and severely impacting quality of life. The invasiveness of in …

[HTML][HTML] Influence of articular cartilage sample geometry on mechanical response and properties using finite element simulation

V Jönsson, GA Orozco, M Pierantoni, H Dejea… - Journal of …, 2024 - Elsevier
Mechanical testing of articular cartilage yields highly variable results, posing challenges for
tissue characterization. Many factors cause variability, one is sample geometry. Using in-situ …

Efficient development of subject-specific finite element knee models: Automated identification of soft-tissue attachments

V Malbouby, KD Gibbons, N Bursa, AK Ivy… - Journal of …, 2025 - Elsevier
Musculoskeletal disorders impact quality of life and incur substantial socio-economic costs.
While in vivo and in vitro studies provide valuable insights, they are often limited by …

A Sensorized 3D-Printed Knee Test Rig for Preliminary Experimental Validation of Patellar Tracking and Contact Simulation

F Michaud, F Mouzo, D Dopico, J Cuadrado - Sensors, 2024 - mdpi.com
Experimental validation of computational simulations is important because it provides
empirical evidence to verify the accuracy and reliability of the simulated results. This …

[PDF][PDF] Machine Learning Model Trained with Finite Element Modeling Can Predict the Risk of Osteoarthritis: Data from the Osteoarthritis Initiative

ME Mononen, MK Liukkonen… - Applied Sciences (2076 …, 2024 - preprints.org
Objective: Despite long simulation times, recently developed finite element analysis (FEA)
models of knee joints have demonstrated their suitability for predicting individual risk of …