Emerging Transcriptional and Genomic Mechanisms Mediating Carbapenem and Polymyxin Resistance in Enterobacteriaceae: a Systematic Review of Current …

M Mmatli, NM Mbelle, NE Maningi, J Osei Sekyere - MSystems, 2020 - Am Soc Microbiol
The spread of carbapenem-and polymyxin-resistant Enterobacteriaceae poses a significant
threat to public health, challenging clinicians worldwide with limited therapeutic options. This …

The balance between antibiotic resistance and fitness/virulence in Pseudomonas aeruginosa: an update on basic knowledge and fundamental research

E Jordana-Lluch, IM Barceló… - Frontiers in …, 2023 - frontiersin.org
The interplay between antibiotic resistance and bacterial fitness/virulence has attracted the
interest of researchers for decades because of its therapeutic implications, since it is …

Carbapenem-resistant Klebsiella pneumoniae: the role of plasmids in emergence, dissemination, and evolution of a major clinical challenge

V Di Pilato, S Pollini, V Miriagou… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction Klebsiella pneumoniae is a major agent of healthcare-associated infections and
a cause of some community-acquired infections, including severe bacteremic infections …

Landscape of plasmids encoding β-lactamases in disinfection residual Enterobacteriaceae from wastewater treatment plants

Z Lin, Z Zhou, X Shuai, G Zeng, R Bao, H Chen - Water Research, 2024 - Elsevier
Conventional disinfection processes, such as chlorination and UV radiation, are ineffective
in controling antibiotic-resistant bacteria, especially disinfection residual Enterobacteriaceae …

Mobile Genetic Elements of Vibrio cholerae and the Evolution of Its Antimicrobial Resistance

R De - Frontiers in Tropical Diseases, 2021 - frontiersin.org
Vibrio cholerae (VC) is the causative agent of the severe dehydrating diarrheal disease
cholera. The primary treatment for cholera is oral rehydration therapy (ORT). However, in …

Co-Existence of Carbapenemase-Encoding Genes in Acinetobacter baumannii from Cancer Patients

R Wasfi, F Rasslan, SS Hassan, HM Ashour… - Infectious Diseases and …, 2021 - Springer
Introduction Acinetobacter baumannii is an opportunistic pathogen, which can acquire new
resistance genes. Infections by carbapenem-resistant A. baumannii (CRAB) in cancer …

Structural Diversity, Fitness Cost, and Stability of a BlaNDM-1-Bearing Cointegrate Plasmid in Klebsiella pneumoniae and Escherichia coli

Z Liu, Z Wang, X Lu, K Peng, S Chen, S He, R Li - Microorganisms, 2021 - mdpi.com
Cointegrate/hybrid plasmids combine the genetic elements of two or more plasmids and
generally carry abundant antimicrobial resistance determinants. Hence, the spread of …

The effects of NDM-5 on Escherichia coli and the screening of interacting proteins

L Li, Y Gao, L Wang, F Lu, Q Ji, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Carbapenem-resistant Escherichia coli (E. coli) strains are widely distributed and spreading
rapidly, creating significant challenges for clinical therapeutics. NDM-5, a novel mutant of …

[HTML][HTML] Distribution of β-lactamases and emergence of carbapenemases co-occurring Enterobacterales isolates with high-level antibiotic resistance identified from …

YC Chen, WY Chen, WY Hsu, HJ Tang, Y Chou… - Journal of Microbiology …, 2022 - Elsevier
Purpose In this study, we aimed to assess the geographic distribution and molecular
characteristics of β-lactamases among Enterobacterales isolates causing intra-abdominal …

Deciphering Multidrug-Resistant Plasmids in Disinfection Residual Bacteria from a Wastewater Treatment Plant

ZJ Lin, ZC Zhou, XY Shuai, XY Shan… - Environmental …, 2024 - ACS Publications
Current disinfection processes pose an emerging environmental risk due to the ineffective
removal of antibiotic-resistant bacteria, especially disinfection residual bacteria (DRB) …