Role of adipose tissue macrophages in obesity-related disorders

S Chakarov, C Blériot, F Ginhoux - Journal of Experimental Medicine, 2022 - rupress.org
The obesity epidemic has led researchers and clinicians to reconsider the etiology of this
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …

Neutrophils actively contribute to obesity-associated inflammation and pathological complications

E Uribe-Querol, C Rosales - Cells, 2022 - mdpi.com
Obesity is characterized by an increase in body weight associated with an exaggerated
enlargement of the adipose tissue. Obesity has serious negative effects because it is …

Leptin: A heavyweight player in obesity-related cancers

A Caruso, L Gelsomino, S Panza, FM Accattatis… - Biomolecules, 2023 - mdpi.com
Obesity, defined as the abnormal or excessive expansion of white adipose tissue, has
reached pandemic proportions and is recognized as an important health concern since it is …

Adipose tissue inflammation: linking physiological stressors to disease susceptibility

BJ Bradford, GA Contreras - Annual Review of Animal …, 2024 - annualreviews.org
The study of adipose tissue (AT) is enjoying a renaissance. White, brown, and beige
adipocytes are being investigated in adult animals, and the critical roles of small depots like …

[HTML][HTML] The interplay between obesity and inflammation

I Savulescu-Fiedler, R Mihalcea, S Dragosloveanu… - Life, 2024 - mdpi.com
Obesity is an important condition affecting the quality of life of numerous patients and
increasing their associated risk for multiple diseases, including tumors and immune …

Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation …

FN Varra, M Varras, VK Varra… - Molecular …, 2024 - spandidos-publications.com
Obesity reaches up to epidemic proportions globally and increases the risk for a wide
spectrum of co-morbidities, including type-2 diabetes mellitus (T2DM), hypertension …

Using adipose‐derived mesenchymal stem cells to fight the metabolic complications of obesity: Where do we stand?

A Mikłosz, BE Nikitiuk, A Chabowski - Obesity Reviews, 2022 - Wiley Online Library
Obesity is a critical risk factor for the development of metabolic diseases, and its prevalence
is increasing worldwide. Stem cell‐based therapies have become a promising tool for …

[HTML][HTML] Clinical perspective on topical vaccination strategies

P Popova, SP Chen, S Liao, M Sadarangani… - Advanced Drug Delivery …, 2024 - Elsevier
Vaccination is one of the most successful measures in modern medicine to combat
diseases, especially infectious diseases, and saves millions of lives every year. Vaccine …

Nonalcoholic fatty liver disease (NAFLD): pathogenesis and noninvasive diagnosis

V Dorairaj, SA Sulaiman, N Abu, NA Abdul Murad - Biomedicines, 2021 - mdpi.com
The global prevalence of nonalcoholic fatty liver disease (NAFLD) or metabolic associated
fatty liver disease (MAFLD), as it is now known, has gradually increased. NAFLD is a …

Understanding the consequences of fatty bone and fatty muscle: how the osteosarcopenic adiposity phenotype uncovers the deterioration of body composition

K Hu, E Deya Edelen, W Zhuo, A Khan, J Orbegoso… - Metabolites, 2023 - mdpi.com
Adiposity is central to aging and several chronic diseases. Adiposity encompasses not just
the excess adipose tissue but also body fat redistribution, fat infiltration, hypertrophy of …