Recently, the increasing prevalence of diabetes mellitus has made it a major chronic illness
which poses a substantial threat to human health. The prevalence of osteoporosis among …

Diabetes mellitus (DM) is a chronic metabolic disorder that can affect the balance of bone
metabolism and bone microenvironment, leading to impaired fracture healing. There are …

The regeneration of diabetic bone defects remains challenging. Hyperglycemia causes
inflammation state and excessive reactive oxygen species (ROS) during bone regeneration …

Diabetes-associated bone complications lead to fragile bone mechanical strength and
osteoporosis, aggravating the disease burden of patients. Advanced evidence shows that …

Objectives Several studies demonstrated a positive relationship between hemoglobin level
and bone mineral density (BMD). Thus, the association between hemoglobin concentration …

Type 2 diabetes mellitus (T2DM) is associated with an increased fracture risk. Our study
aimed to explore differences in bone alterations between T2DM women and controls and to …

Disturbed glucose metabolism in diabetes mellitus (DM) patients affects bone metabolism
and its microenvironment, which significantly impaired bone regeneration, making bone …

Type 2 diabetes mellitus (T2DM) causes an increased risk of bone fractures. However, the
pathophysiology of diabetic bone fragility is not completely understood. It has been …

Increased bone fragility and poor bone healing are common and serious complications of
diabetes, especially in elderly patients. Long-term hyperglycemia often leads to serious …

Increased risks of skeletal fractures are common in patients with impaired glucose handling
and type 2 diabetes mellitus (T2DM). The pathogenesis of skeletal fragility in these patients …