Philadelphia chromosome-negative classical myeloproliferative neoplasms: revised management recommendations from European LeukemiaNet

T Barbui, A Tefferi, AM Vannucchi, F Passamonti… - Leukemia, 2018 - nature.com
This document updates the recommendations on the management of Philadelphia
chromosome-negative myeloproliferative neoplasms (Ph-neg MPNs) published in 2011 by …

Polycythemia vera: historical oversights, diagnostic details, and therapeutic views

A Tefferi, AM Vannucchi, T Barbui - Leukemia, 2021 - nature.com
Polycythemia vera (PV) is a relatively indolent myeloid neoplasm with median survival that
exceeds 35 years in young patients, but its natural history might be interrupted by …

Polycythemia vera: 2024 update on diagnosis, risk‐stratification, and management

A Tefferi, T Barbui - American journal of hematology, 2023 - Wiley Online Library
Abstract Disease Overview Polycythemia vera (PV) is a JAK2‐mutated myeloproliferative
neoplasm characterized by clonal erythrocytosis; other features include leukocytosis …

Risk for arterial and venous thrombosis in patients with myeloproliferative neoplasms: a population-based cohort study

M Hultcrantz, M Björkholm, PW Dickman… - Annals of internal …, 2018 - acpjournals.org
Background: Patients with myeloproliferative neoplasms (MPNs) are reported to be at
increased risk for thrombotic events. However, no population-based study has estimated this …

Ropeginterferon alfa-2b versus phlebotomy in low-risk patients with polycythaemia vera (Low-PV study): a multicentre, randomised phase 2 trial

T Barbui, AM Vannucchi, V De Stefano… - The Lancet …, 2021 - thelancet.com
Background There is no evidence that phlebotomy alone is sufficient to steadily maintain
haematocrit on target level in low-risk patients with polycythaemia vera. This study aimed to …

Myeloproliferative neoplasms: a contemporary review

A Tefferi, A Pardanani - JAMA oncology, 2015 - jamanetwork.com
Polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF)
constitute theBCR-ABL1–negative myeloproliferative neoplasms and are characterized by …

Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk‐stratification, and management

A Tefferi, T Barbui - American journal of hematology, 2017 - Wiley Online Library
Abstract Disease overview Polycythemia Vera (PV) and essential thrombocythemia (ET) are
myeloproliferative neoplasms respectively characterized by erythrocytosis and …

Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk‐stratification and management

A Tefferi, T Barbui - American journal of hematology, 2015 - Wiley Online Library
Disease overview: Polycythemia vera (PV) and essential thrombocythemia (ET) are
myeloproliferative neoplasms, respectively characterized by erythrocytosis and …

Myeloproliferative neoplasms: a decade of discoveries and treatment advances

A Tefferi - American journal of hematology, 2016 - Wiley Online Library
Myeloproliferative neoplasms (MPN) are clonal stem cell diseases, first conceptualized in
1951 by William Dameshek, and historically included chronic myeloid leukemia (CML) …

Neutrophil-to-lymphocyte ratio is a novel predictor of venous thrombosis in polycythemia vera

A Carobbio, AM Vannucchi, V De Stefano… - Blood cancer …, 2022 - nature.com
We investigated the neutrophil-to-lymphocyte ratio (NLR) as a predictor of thrombosis in
polycythemia vera (PV). After a median follow-up of 2.51 years, of 1508 PV patients enrolled …