[HTML][HTML] Oocyte selection for in vitro embryo production in bovine species: noninvasive approaches for new challenges of oocyte competence

L Aguila, F Treulen, J Therrien, R Felmer, M Valdivia… - Animals, 2020 - mdpi.com
Simple Summary The efficiency of producing embryos using in vitro technologies in cattle
species remains lower when compared to mice, indicating that the proportion of female …

DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies

R Musson, Ł Gąsior, S Bisogno… - Human Reproduction …, 2022 - academic.oup.com
BACKGROUND DNA damage is a hazard that affects all cells of the body. DNA-damage
repair (DDR) mechanisms are in place to repair damage and restore cellular function, as are …

Long term effects of ART: What do animals tell us?

V Duranthon, P Chavatte‐Palmer - Molecular Reproduction and …, 2018 - Wiley Online Library
Early stages of mammalian embryonic development are now known to be very sensitive to
their microenvironment, with long term effects on fetal, postnatal, and adult health, thus …

[HTML][HTML] Role of lipid metabolism and signaling in mammalian oocyte maturation, quality, and acquisition of competence

R Khan, X Jiang, U Hameed, Q Shi - Frontiers in cell and …, 2021 - frontiersin.org
It has been found that the quality of oocytes from obese women has been compromised and
subsequent embryos displayed arrested development. The compromised quality may be …

Dynamic metabolism during early mammalian embryogenesis

J Zhao, W Wang, L Zhang, J Zhang, R Sturmey… - …, 2023 - journals.biologists.com
Dynamic metabolism is exhibited by early mammalian embryos to support changing cell
fates during development. It is widely acknowledged that metabolic pathways not only satisfy …

Non-invasive oocyte quality assessment

R Sciorio, D Miranian, GD Smith - Biology of Reproduction, 2022 - academic.oup.com
Oocyte quality is perhaps the most important limiting factor in female fertility; however, the
current methods of determining oocyte competence are only marginally capable of …

[HTML][HTML] Raman microspectroscopy fingerprinting of organoid differentiation state

K Tubbesing, N Moskwa, TC Khoo, DA Nelson… - Cellular & Molecular …, 2022 - Springer
Background Organoids, which are organs grown in a dish from stem or progenitor cells,
model the structure and function of organs and can be used to define molecular events …

[HTML][HTML] Coherent Raman scattering microscopy for chemical imaging of biological systems

C Zhang, JA Aldana-Mendoza - Journal of Physics: Photonics, 2021 - iopscience.iop.org
Coherent Raman scattering (CRS) processes, including both the coherent anti-Stokes
Raman scattering and stimulated Raman scattering, have been utilized in state-of-the-art …

[HTML][HTML] Quantitative label-free imaging of iron-bound transferrin in breast cancer cells and tumors

TC Khoo, K Tubbesing, A Rudkouskaya, S Rajoria… - Redox Biology, 2020 - Elsevier
Transferrin (Tf) is an essential serum protein which delivers iron throughout the body via
transferrin-receptor (TfR)-mediated uptake and iron release in early endosomes. Currently …

Iron-binding cellular profile of transferrin using label-free Raman hyperspectral imaging and singular value decomposition (SVD)

K Tubbesing, TC Khoo, SB Jangjoo, A Sharikova… - Free Radical Biology …, 2021 - Elsevier
Serum transferrin (Tf) is the essential iron transport protein in the body. Transferrin is
responsible for the sequestration of free iron in serum and the delivery of iron throughout the …