Tissue repair after trauma and infection has always been a difficult problem in regenerative
medicine. Hydrogels have become one of the most important scaffolds for tissue …

Over the last decade, numerous biopolymers have received more attention in medical
applications involving novel biomaterials because of their biocompatibility, biodegradability …

Silk fibroin (SF) was enzymatically crosslinked with tyramine-substituted silk fibroin (SF-TA)
or gelatin (G-TA) to fabricate hybrid hydrogels with tunable gelation kinetics, mechanical …

To investigate how cells sense stiffness in settings structurally similar to native extracellular
matrices, we designed a synthetic fibrous material with tunable mechanics and user-defined …

Injectable hydrogels with biodegradability have in situ formability which in vitro/in vivo allows
an effective and homogeneous encapsulation of drugs/cells, and convenient in vivo surgical …

The conjugation of biomolecules can impart materials with the bioactivity necessary to
modulate specific cell behaviors. While the biological roles of particular polypeptide …

Stem cell behaviors are regulated by multiple microenvironmental cues. As an external
signal, mechanical stiffness of the extracellular matrix is capable of governing stem cell fate …

Mechanics is an important component in the regulation of cell shape, proliferation, migration
and differentiation during normal homeostasis and disease states. Biomaterials that match …

Millions of people lose or damage their organs or tissues due to disease, birth defects, or
accidents each year. Stem cells, such as embryonic stem cells (ESCs), induced pluripotent …

Biomimetic hybrid hydrogels have generated broad interest in tissue engineering and
regenerative medicine. Hyaluronic acid (HA) and gelatin (hydrolyzed collagen) are naturally …