Unraveling the role of natural killer cells in leishmaniasis

Z Alizadeh, P Omidnia, FMA Altalbawy, GA Gabr… - International …, 2023 - Elsevier
NK cells are known as frontline responders that are efficient in combating several maladies
as well as leishmaniasis caused by Leishmania spp. As such they are being investigated to …

The Dual Function of RhoGDI2 in Immunity and Cancer

M Tripathi, A Colige, CF Deroanne - International Journal of Molecular …, 2023 - mdpi.com
RhoGDI2 is a guanine nucleotide dissociation inhibitor (GDI) specific for the Rho family of
small GTPases. It is highly expressed in hematopoietic cells but is also present in a large …

Coronavirus-19 disease risk and protective factors associated with HLA/KIR polymorphisms in Ecuadorian patients residing in Madrid

A Balas, MÁ Moreno-Hidalgo, F de la Calle-Prieto… - Human Immunology, 2023 - Elsevier
Abstract Background Immigrants represented 21.8% of cases in a Spanish cohort of
hospitalised patients with COVID-19, a proportion exceeding the percentage of immigrants …

Inhibition of ERAP1 represses HLA-B27 free heavy chains expression on polarized macrophages and interrupts NK cells activation and function from ankylosing …

F Babaie, H Mohammadi, S Salimi… - Clinical …, 2023 - Elsevier
Background We aimed to assess if Endoplasmic reticulum aminopeptidase 1 (ERAP1)
polymorphisms might impress Human leukocyte antigen (HLA)-B27-free heavy chains …

Natural killer cells in peripheral blood at diagnosis predict response to immunosuppressive therapy in severe aplastic anemia

W Yu, Q Wang, M Ge, X Shi - Clinical and Experimental Medicine, 2023 - Springer
Immunosuppressive therapy (IST) consisting of antihuman thymocyte globulin and
cyclosporine A is the first-line therapy for patients with severe aplastic anemia (AA) who are …

Genetic variability of three common NK and γδ T cell receptor genes (FCγ3R, NCR3, and DNAM-1) and their role in Polish patients with rheumatoid arthritis and …

S Biały, M Iwaszko, J Świerkot, K Kolossa… - Immunologic …, 2024 - Springer
Various lymphocyte subpopulations, including NK cells as well as γδ T cells, have been
considered an important element in the pathogenesis of autoimmune, inflammatory …

Interleukin 23 receptor gene polymorphisms and their role in the inflammatory status of rheumatoid arthritis patients in an Iranian population

M Abbasifard, MR Mirzaei, M Abade… - International Journal …, 2023 - Wiley Online Library
Background Several investigations have disclosed the involvement of the interleukin (IL)‐
23/IL‐17 pathway in rheumatoid arthritis (RA) pathogenesis. Here we investigated the …

MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis

M Hemmatzadeh, EA Parvin… - Iranian Journal of …, 2022 - ijaai.tums.ac.ir
Natural killer (NK) cells play a role in the pathogenesis of rheumatoid arthritis (RA).
Upregulated levels of programmed cell death protein 1 (PD-1) is a sign of exhausted NK …