Abstract α‐Arylated carbonyl compounds are commonly occurring motifs in biologically
interesting molecules and are therefore of high interest to the pharmaceutical industry …

Abstract In α‐Stellung arylierte Carbonyleinheiten sind in biologisch interessanten
Molekülen häufig vertreten und daher von großem Interesse für die pharmazeutische …

The considerable importance of α-arylated carbonyl compounds, which are widely used as
final products or as key intermediates in the pharmaceutical industry, has prompted …

N‐Propargyl‐and N‐homoallenyl‐2‐bromo‐β‐tryptamines undergo gold (I)‐catalyzed
dearomatizing cyclizations to afford 2‐bromospiroindolenines that are in situ hydrolyzed to …

Drug structures may be quantitatively compared based on 2D topological structural
considerations and based on 3D characteristics directly related to binding. A framework for …

Treatment of N-arylisonicotinamides with trifluoromethanesulfonic anhydride triggers
intramolecular nucleophilic attack of the aryl ring on the 4-position of the pyridinium …

3,666,764 A 5/1972 Campbell et al. 3,959.475 A 5, 1976 Bauer et al. 3,962,259 A 6, 1976
Bauer et al. 4,233,307 A 11, 1980 Ono et al. 4,349,549 A 9, 1982 Roszkowski et al …

To identify selective high-affinity inhibitors of the vesicular acetylcholine transporter
(VAChT), we have interposed a carbonyl group between the phenyl and piperidyl groups of …

An efficient procedure for the synthesis of spiro [furan-3, 3′-indolin]-2-ones and dispiro
[cycloalkane-1, 2′-furan-3′, 3 ″-indolin]-2 ″-ones has been achieved in high yields and …

A series of highly functionalized dispiro [3H-indole-3, 2′-pyrrolidine-3′, 3′′-piperidine]-
2 (1H), 4′′-dione derivatives have been synthesized in good to excellent yields by one …