Bioassay-guided isolation based on the antifungal activity of a culture broth of the marine-
derived actinomycete Streptomyces caniferus CA-271066 led to the discovery of new 36 …

Epoxides are privileged and valuable electrophiles frequently utilized as versatile building
blocks in synthetic chemistry to prepare diverse alcohols through ring-opening reactions …

Herein, a convenient hydrodehalogenation method was described by employing less-
explored calcium hydride as the reductant. A wide range of organic halides such as aromatic …

Using the DP4f GIAO-NMR method, the stereochemistry of hemicalide was computationally
analysed, resulting in a reassignment at C18 as supported by improved NMR shift …

Dideoxy sugars constitute an important class of anticancer antibiotics natural products and
serve as essential medicinal tools for carbohydrate-based drug discovery and vaccine …

This is a review of papers published in the year 2015 that focus on the synthesis, reactivity,
or properties of compounds containing a carbon-transition metal double or triple bond …

Gargantulides B and C, two new and highly complex 52-membered glycosylated
macrolactones, were isolated from Amycolatopsis sp. strain CA-230715 during an …

The first total synthesis and structure revision of (−)-11β-hydroxycurvularin (1b), a macrolide
possessing a β-hydroxyketone moiety, were accomplished. The β-hydroxyketone moiety in …

This review highlights the various challenges overcome during our recent synthetic
campaign towards (−)‐leiodermatolide, a potent cytotoxic and antimitotic macrolide isolated …

The synthesis of the C1–C27 fragment of hemicalide, a marine metabolite displaying a
unique potent antiproliferative activity, has been accomplished. The synthetic approach …