The potential protective role of carotenoids from saffron: A focus on endoplasmic reticulum stress‐related organ damage

F Mirzavi, A Rajabian, H Hosseini - Food Science & Nutrition, 2024 - Wiley Online Library
The anticancer, antioxidant, and immunomodulatory properties of carotenoids from saffron
or apocarotenoids (eg, crocin, safranal, crocetin, and picrocrocin) have prompted research …

Pulmonary toxicity and proteomic analysis in bronchoalveolar lavage fluids and lungs of rats exposed to copper oxide nanoparticles

JT Kwon, Y Kim, S Choi, B Yoon, HS Kim… - International journal of …, 2022 - mdpi.com
Copper oxide nanoparticles (CuO NPs) were intratracheally instilled into lungs at
concentrations of 0, 0.15, and 1.5 mg/kg bodyweight to 7-week-old Sprague–Dawley rats …

Uncovering biodegradability and biocompatibility of betaine-based deep eutectic systems

IJ Ferreira, A Paiva, M Diniz, AR Duarte - Environmental Science and …, 2023 - Springer
Deep eutectic systems (DES) have shown increasing popularity in last decade; however, the
number of studies on the potential toxicity towards living organisms remains scarce. These …

Neuroprotective assessment of betaine against copper oxide nanoparticle-induced neurotoxicity in the brains of albino rats: a histopathological, neurochemical, and …

AR Hashim, DW Bashir, E Rashad… - ACS Chemical …, 2024 - ACS Publications
Copper oxide nanoparticles (CuO-NPs) are commonly used metal oxides. Betaine
possesses antioxidant and neuroprotective activities. The current study aimed to investigate …

Preclinical Evaluation of Protective Effects of Terpenoids Against Nanomaterial‐Induced Toxicity: A Meta‐Analysis

Y Sun, Y Zhou, D Xie, X Wang, Y Wang… - Journal of Applied …, 2024 - Wiley Online Library
Terpenoids, the largest class of natural products, have been demonstrated to confer
antioxidant, anti‐inflammatory, anti‐apoptotic, and antitumor activities. However, whether …

Prepubertal exposure to copper oxide nanoparticles induces Leydig cell injury with steroidogenesis disorders in mouse testes

X Zheng, J Chen, L Kang, Y Wei, Y Wu, Y Hong… - Biochemical and …, 2023 - Elsevier
Copper oxide nanoparticles (CuONPs) are metallic multifunctional nanoparticles with good
conductive, catalytic and antibacterial characteristics that have shown to cause reproductive …

Histotoxicity induced by copper oxide nanoparticles (CuO-NPs) on developing mice (Mus musculus)

M Ahmad, MKA Khan, N Ahmad, M Parveen… - Food and Chemical …, 2024 - Elsevier
The wide range of applications of nanoparticles (NPs) in various industries have led to
serious consequences in terms of teratogenic toxicity. The aim of current work was to …

Alleviative effect of betaine against copper oxide nanoparticles-induced hepatotoxicity in adult male albino rats: histopathological, biochemical, and molecular studies

AR Hashim, DW Bashir, E Rashad, MK Galal… - Beni-Suef University …, 2024 - Springer
Abstract Background Copper oxide nanoparticles (CuO-NPs) have gained interest due to
their availability, efficiency, and their cost-effectiveness. Betaine is an essential methyl donor …

Crocin, a bioactive constituent of Crocus sativus, alleviates trimethyltin-induced cognitive deficits through down-regulation of hippocampal apoptosis and oxidative …

S Ghofrani, MT Joghataei… - Journal of Basic …, 2022 - journals.shahed.ac.ir
Background and Objective: Cognitive deficits are associated with neurodegenerative
disorders including Alzheimer's disease (AD). Trimethyltin chloride (TMT) with potent …

Investigating the effect of PHR 160 spray on the laboratory results of patients with covid-19-a randomized clinical trial study-Supplementary results

M Bagheri, M Asghardoust Rezaei, M Raei… - International Journal of …, 2024 - ijtmgh.com
Background and aims: One of the recommended treatment methods for covid-19 is herbal
treatments, which, if used, can be used as an effective preventive or supportive treatment in …