Hydroxypropionic acid (3-HP) is a valuable platform chemical that can be produced
biologically from glucose or glycerol. This review article provides an overview and the …

Bacterial microcompartments (MCPs) are sophisticated protein-based organelles used to
optimize metabolic pathways. They consist of metabolic enzymes encapsulated within a …

Using comparative analysis of genes, operons, and regulatory elements, we describe the
cobalamin (vitamin B 12) biosynthetic pathway in available prokaryotic genomes. Here we …

The propanediol utilization (pdu) operon of Salmonella enterica serovar Typhimurium LT2
contains genes needed for the coenzyme B12-dependent catabolism of 1, 2-propanediol …

Lactobacillus reuteri is a heterofermentative lactic acid bacterium that naturally inhabits the
gut of humans and other animals. The probiotic effects of L. reuteri have been proposed to …

Abstract Background Nickel (Ni) and cobalt (Co) are trace elements required for a variety of
biological processes. Ni is directly coordinated by proteins, whereas Co is mainly used as a …

Coenzyme B12 or adenosylcobalamin (AdoCbl)(Figure 1A), a naturally occurring
organometallic compound that contains a unique Co-C σ bond, serves as a cofactor for …

INTRODUCTION The microbes that live in and on our bodies (the human microbiome)
profoundly affect human health and disease. For example, within the lower gastrointestinal …

Hydroxypropionaldehyde (3-HPA) forms, together with HPA-hydrate and HPA-dimer, a
dynamic, multi-component system (HPA system) used in food preservation, as a precursor …

Corynebacterium glutamicum is a versatile chassis which has been widely used to produce
various amino acids and organic acids. In this study, we report the development of an …