Endothelial dysfunction in hypertension: current concepts and clinical implications
Endothelium plays a fundamental role in the cardiovascular system, forming an interface
between blood and adjacent tissues by regulating the vascular tone through the synthesis of …
between blood and adjacent tissues by regulating the vascular tone through the synthesis of …
Extracellular vesicles as personalized medicine
Extracellular vesicles (EVs) are released from all cells in the body, forming an important
intercellular communication network that contributes to health and disease. The contents of …
intercellular communication network that contributes to health and disease. The contents of …
Extracellular vesicles and their emerging roles as cellular messengers in endocrinology: an endocrine society scientific statement
During the last decade, there has been great interest in elucidating the biological role of
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …
Mechanisms and clinical implications of endothelial dysfunction in arterial hypertension
P Ambrosino, T Bachetti, SE D'Anna… - Journal of …, 2022 - mdpi.com
The endothelium is composed of a monolayer of endothelial cells, lining the interior surface
of blood and lymphatic vessels. Endothelial cells display important homeostatic functions …
of blood and lymphatic vessels. Endothelial cells display important homeostatic functions …
In sickness and in health: The functional role of extracellular vesicles in physiology and pathology in vivo: Part I: Health and Normal Physiology
Previously thought to be nothing more than cellular debris, extracellular vesicles (EVs) are
now known to mediate physiological and pathological functions throughout the body. We …
now known to mediate physiological and pathological functions throughout the body. We …
Targeting SIRT1 rescues age-and obesity-induced microvascular dysfunction in ex vivo human vessels
Background: Experimental evidence suggests a key role of SIRT1 (silent information
regulator 1) in age-and metabolic-related vascular dysfunction. Whether these effects hold …
regulator 1) in age-and metabolic-related vascular dysfunction. Whether these effects hold …
Role of extracellular vesicles in the pathogenesis of vascular damage
Extracellular vesicles (EVs) are nanosized membrane-bound structures released by cells
that are able to transfer nucleic acids, protein cargos, and metabolites to specific recipient …
that are able to transfer nucleic acids, protein cargos, and metabolites to specific recipient …
Diagnostic and Therapeutic Roles of Extracellular Vesicles in Aging‐Related Diseases
Z Sun, X Hou, J Zhang, J Li, P Wu… - … medicine and cellular …, 2022 - Wiley Online Library
Aging shows a decline in overall physical function, and cellular senescence is the powerful
catalyst leading to aging. Considering that aging will be accompanied with the emergence of …
catalyst leading to aging. Considering that aging will be accompanied with the emergence of …
Insight into extracellular vesicles in vascular diseases: intercellular communication role and clinical application potential
W Liu, M Jin, Q Chen, Q Li, X Xing, Y Luo… - Cell Communication and …, 2023 - Springer
Background Cells have been increasingly known to release extracellular vesicles (EVs) to
the extracellular environment under physiological and pathological conditions. A plethora of …
the extracellular environment under physiological and pathological conditions. A plethora of …
Message in a bubble: the translational potential of extracellular vesicles
H Alqurashi, M Alsharief, ML Perciato… - The Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are small, membrane‐enclosed vesicles released by cells into
the extracellular milieu. They are found in all body fluids and contain a variety of functional …
the extracellular milieu. They are found in all body fluids and contain a variety of functional …