Nanoengineered immune niches for reprogramming the immunosuppressive tumor microenvironment and enhancing cancer immunotherapy

H Phuengkham, L Ren, IW Shin, YT Lim - Advanced Materials, 2019 - Wiley Online Library
Cancer immunotherapies that harness the body's immune system to combat tumors have
received extensive attention and become mainstream strategies for treating cancer. Despite …

Nanoparticle drug delivery systems designed to improve cancer vaccines and immunotherapy

Y Fan, JJ Moon - Vaccines, 2015 - mdpi.com
Recent studies have demonstrated great therapeutic potential of educating and unleashing
our own immune system for cancer treatment. However, there are still major challenges in …

Nano-, micro-, and macroscale drug delivery systems for cancer immunotherapy

P Huang, X Wang, X Liang, J Yang, C Zhang, D Kong… - Acta biomaterialia, 2019 - Elsevier
Immunotherapy is moving to the frontier of cancer treatment. Drug delivery systems (DDSs)
have greatly advanced the development of cancer immunotherapeutic regimen and …

[HTML][HTML] Doxil synergizes with cancer immunotherapies to enhance antitumor responses in syngeneic mouse models

J Rios-Doria, N Durham, L Wetzel, R Rothstein… - Neoplasia, 2015 - Elsevier
Based on the previously described roles of doxorubicin in immunogenic cell death, both
doxorubicin and liposomal doxorubicin (Doxil) were evaluated for their ability to boost the …

Precise delivery of nanomedicines to M2 macrophages by combining “Eat Me/Don't Eat Me” signals and its anticancer application

Y Tang, Z Tang, P Li, K Tang, Z Ma, Y Wang, X Wang… - ACS …, 2021 - ACS Publications
Targeted delivery of nanomedicines to M2 tumor-associated macrophages (TAMs) has been
proposed to reduce tumor promotion and enhance the efficacy of anticancer therapy …

Overview on therapeutic applications of microparticulate drug delivery systems

S Bale, A Khurana, ASS Reddy… - Critical Reviews™ in …, 2016 - dl.begellhouse.com
Research in novel drug delivery systems is being explored competitively in order to attain
maximum therapeutic effect while minimizing the adverse effects. Despite several …

Antibody opsonization of a TLR9 agonist–containing virus-like particle enhances in situ immunization

CD Lemke-Miltner, SE Blackwell, C Yin… - The Journal of …, 2020 - journals.aai.org
The immunologic and therapeutic effects of intratumoral (IT) delivery of a novel virus-like
particle as a lymphoma immunotherapy were evaluated in preclinical studies with human …

Chemical synthesis, versatile structures and functions of tailorable adjuvants for optimizing oral vaccination

L Zhang, C Hu, W Yang, X Liu, Y Wu - ACS Applied Materials & …, 2016 - ACS Publications
Oral vaccines have become a recent focus because of their potential significance in disease
prevention and therapy. In the development of oral vaccine-based therapeutics, synthetic …

Antitumor immune responses induced by photodynamic and sonodynamic therapy: a narrative review

H Chen, Z Dai - Journal of Bio-X Research, 2021 - spj.science.org
The immune system has the function of immune surveillance to resist the occurrence and
development of tumors, and is essential for inhibition of tumor metastasis. Nevertheless …

[HTML][HTML] Spontaneous Regression of Diffuse Large B-cell Lymphoma in a Patient with Ataxia–Telangiectasia

R Sherkat, NA Moghaddam, N Reisi… - Advanced Biomedical …, 2022 - journals.lww.com
Ataxia–telangiectasia (AT) is a type of primary immunodeficiency characterized by an
autosomal recessive mode of inheritance and usually presents with progressive cerebellar …