A single-cell atlas and lineage analysis of the adult Drosophila ovary

K Rust, LE Byrnes, KS Yu, JS Park, JB Sneddon… - Nature …, 2020 - nature.com
The Drosophila ovary is a widely used model for germ cell and somatic tissue biology. Here
we use single-cell RNA-sequencing (scRNA-seq) to build a comprehensive cell atlas of the …

A single-cell atlas of adult Drosophila ovary identifies transcriptional programs and somatic cell lineage regulating oogenesis

A Jevitt, D Chatterjee, G Xie, XF Wang, T Otwell… - PLOS …, 2020 - journals.plos.org
Oogenesis is a complex developmental process that involves spatiotemporally regulated
coordination between the germline and supporting, somatic cell populations. This process …

Automatic stage identification of Drosophila egg chamber based on DAPI images

D Jia, Q Xu, Q Xie, W Mio, WM Deng - Scientific reports, 2016 - nature.com
The Drosophila egg chamber, whose development is divided into 14 stages, is a well-
established model for developmental biology. However, visual stage determination can be a …

A Genetic Mosaic Screen Reveals Ecdysone-Responsive Genes Regulating Drosophila Oogenesis

ET Ables, GH Hwang, DS Finger… - G3: Genes …, 2016 - academic.oup.com
Multiple aspects of Drosophila oogenesis, including germline stem cell activity, germ cell
differentiation, and follicle survival, are regulated by the steroid hormone ecdysone. While …

Developmental regulation of epithelial cell cuboidal-to-squamous transition in Drosophila follicle cells

D Jia, A Jevitt, YC Huang, B Ramos, WM Deng - Developmental biology, 2022 - Elsevier
Epithelial cells form continuous membranous structures for organ formation, and these cells
are classified into three major morphological categories: cuboidal, columnar, and …

Aedes aegypti antiviral adaptive response against DENV-2

J Serrato-Salas, J Izquierdo-Sánchez… - Developmental & …, 2018 - Elsevier
Priming is the conceptual term defining memory phenomenon in innate immune response.
Numerous examples of enhanced secondary immune response have been described in …

NOTCH2/NOTCH3/DLL3/MAML1/ADAM17 signaling network is associated with ovarian cancer

D Jia, J Underwood, Q Xu, Q Xie - Oncology Letters, 2019 - spandidos-publications.com
Notch signaling is well‑known for its role in regulating cell self‑renewal and differentiation.
Within the cancer research field, it has been identified that dysregulated Notch signaling is …

Developmental regulation of regenerative potential in Drosophila by ecdysone through a bistable loop of ZBTB transcription factors

K Narbonne-Reveau, C Maurange - PLoS biology, 2019 - journals.plos.org
In many organisms, the regenerative capacity of tissues progressively decreases as
development progresses. However, the developmental mechanisms that restrict …

A large-scale in vivo RNAi screen to identify genes involved in Notch-mediated follicle cell differentiation and cell cycle switches

D Jia, M Soylemez, G Calvin, R Bornmann, J Bryant… - Scientific reports, 2015 - nature.com
During Drosophila oogenesis, follicle cells sequentially undergo three distinct cell-cycle
programs: the mitotic cycle, endocycle and gene amplification. Notch signaling plays a …

Analysis of Cell Cycle Switches in Drosophila Oogenesis

D Jia, YC Huang, WM Deng - Drosophila Oogenesis: Methods and …, 2015 - Springer
The study of Drosophila oogenesis provides invaluable information about signaling pathway
regulation and cell cycle programming. During Drosophila oogenesis, a string of egg …