Type 1 diabetes is an autoimmune disorder in which the immune system attacks and
destroys insulin-producing islet cells of the pancreas. Although islet transplantation has …

Purpose: To determine the mechanism of blood-retinal barrier (BRB) dysfunction in human
and experimental specimens using immunocytochemistry. Methods: Extravascular albumin …

Cerebral expression of the injury response cytokine transforming growth factor-β1 (TGF-β1)
has been found to be increased in several neurological diseases but it remains unclear …

Characterised by intraocular inflammation, non‐infectious uveitis includes a large group of
autoimmune and autoinflammatory diseases that either involve the eye alone or have both …

Atherosclerotic vascular calcification contributes to increased risk of death in patients with
cardiovascular diseases. Assessing the type and severity of inflammation is crucial in the …

Recent breakthroughs in our understanding of the molecular pathophysiology of retinal
vascular disease have allowed us to specifically target pathological angiogenesis while …

The contribution of inflammation to deleterious aging outcomes is increasingly recognized;
however, little is known about the complex relationship between interleukin-6 (IL-6) and …

Advances in the field of tissue engineering have enhanced the potential of regenerative
medicine, yet the efficacy of these strategies remains incomplete, and is limited by the innate …

We investigated the effectiveness of lipopolysaccharide (LPS) and muramyl dipeptide (MDP)
administered into the brain to induce anorexia in acutely fasted Wistar rats allowed to refeed …

Protracted systemic inflammation has been associated with adverse effects on cognition and
brain structure and may accelerate neurodegenerative disease processes; however, it is …