Review of Molecular Technologies for Investigating Canine Cancer

A Kehl, H Aupperle-Lellbach, S de Brot… - Animals, 2024 - mdpi.com
Simple Summary Genetic molecular testing is starting to become part of standard clinical
practice for dogs with cancer as it can assist veterinarians with diagnosis, provide …

An Evolutionary Perspective on Dog Behavioral Genetics

KA Lord, FL Chen, EK Karlsson - Annual Review of Animal …, 2024 - annualreviews.org
Dogs have played an outsized role in the field of behavioral genetics since its earliest days.
Their unique evolutionary history and ubiquity in the modern world make them a potentially …

Historic dog furs unravel the origin and artificial selection of modern Nordic Lapphund and Elkhound dog breeds

SZ Wang, Y Yan, M Widlund, CC Qian… - Molecular biology …, 2024 - academic.oup.com
The origins and extreme morphological evolution of the modern dog breeds are poorly
studied because the founder populations are extinct. Here, we analyse eight 100 to 200 …

Acquired dysfunction of CFTR underlies cystic fibrosis-like disease of the canine gallbladder

JL Gookin, J Holmes, LL Clarke… - American Journal …, 2024 - journals.physiology.org
Mucocele formation in dogs is a unique and enigmatic muco-obstructive disease of the
gallbladder caused by the amassment of abnormal mucus that bears striking pathological …

The DoGA consortium expression atlas of promoters and genes in 100 canine tissues

M Hörtenhuber, MK Hytönen, AK Mukarram… - Nature …, 2024 - nature.com
The dog, Canis lupus familiaris, is an important model for studying human diseases. Unlike
many model organisms, the dog genome has a comparatively poor functional annotation …

Genome-wide analyses reveals an association between invasive urothelial carcinoma in the Shetland sheepdog and NIPAL1

HG Parker, AC Harris, J Plassais, D Dhawan… - npj Precision …, 2024 - nature.com
Naturally occurring canine invasive urinary carcinoma (iUC) closely resembles human
muscle invasive bladder cancer in terms of histopathology, metastases, response to therapy …

Online Mendelian Inheritance in Animals (OMIA): a genetic resource for vertebrate animals

I Tammen, M Mather, T Leeb, FW Nicholas - Mammalian Genome, 2024 - Springer
Abstract Online Mendelian Inheritance in Animals (OMIA) is a freely available curated
knowledgebase that contains information and facilitates research on inherited traits and …

Dog10K: an integrated Dog10K database summarizing canine multi-omics

T Zhou, SY Pu, SJ Zhang, QJ Zhou, M Zeng… - Nucleic Acids …, 2024 - academic.oup.com
The diversity observed in canine breed phenotypes, together with their risk for heritabily
disorders of relevance to dogs and humans, makes the species an ideal subject for studies …

[HTML][HTML] Exonic Short Interspersed Nuclear Element Insertion in FAM161A Is Associated with Autosomal Recessive Progressive Retinal Atrophy in the English …

K Stanbury, EC Schofield, B McLaughlin, OP Forman… - Genes, 2024 - mdpi.com
Progressive retinal atrophies (PRAs) are a genetically heterogeneous group of inherited eye
diseases that affect over 100 breeds of dog. The initial clinical sign is visual impairment in …

iDog: a multi-omics resource for canids study

Y Liu, Y Wang, J Sun, D Kong, B Zhou… - Nucleic Acids …, 2024 - academic.oup.com
Abstract iDog (https://ngdc. cncb. ac. cn/idog/) is a comprehensive public resource for
domestic dogs (Canis lupus familiaris) and wild canids, designed to integrate multi-omics …