[HTML][HTML] Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential

YS Fu, TH Chen, L Weng, L Huang, D Lai… - Biomedicine & …, 2021 - Elsevier
Curcumin, isolated from Curcuma longa L., is a fat-soluble natural compound that can be
obtained from ginger plant tuber roots, which accumulative evidences have demonstrated …

Application of curcumin nanoformulations to target folic acid receptor in cancer: Recent trends and advances

A Hussain, A Kumar, V Uttam, U Sharma, K Sak… - Environmental …, 2023 - Elsevier
Curcumin, derived from turmeric, has a strong anticancer potential known for millennia. The
development of this phytochemical as a medicine has been hampered by several significant …

Nano-curcumin supplementation in critically ill patients with sepsis: a randomized clinical trial investigating the inflammatory biomarkers, oxidative stress indices …

A Karimi, F Naeini, HR Niazkar, H Tutunchi… - Food & function, 2022 - pubs.rsc.org
Sepsis is a severe reaction and excessive immune response to infection, which can lead to
organ dysfunction, and death. This study aimed to investigate the protective effect of nano …

Therapeutic potential and recent advances of curcumin in the treatment of aging-associated diseases

S Sundar Dhilip Kumar, NN Houreld, H Abrahamse - Molecules, 2018 - mdpi.com
Curcumin, a low molecular weight, lipophilic, major yellow natural polyphenolic, and the
most well-known plant-derived compound, is extracted from the rhizomes of the turmeric …

Natural tyrosine kinase inhibitors acting on the epidermal growth factor receptor: Their relevance for cancer therapy

Y Liang, T Zhang, J Zhang - Pharmacological Research, 2020 - Elsevier
Epidermal growth factor receptor (EGFR), also known as ErbB-1/HER-1, plays a key role in
the regulation of the cell proliferation, migration, differentiation, and survival. Since the …

[HTML][HTML] Medicinal plants for gingivitis: a review of clinical trials

H Safiaghdam, V Oveissi, R Bahramsoltani… - Iranian journal of …, 2018 - ncbi.nlm.nih.gov
Objective (s): Periodontal diseases are among prevalent oral health problems which may
ultimately lead to severe complications in oral cavity. Herbal products can be designed as …

Curcumin-loaded mesoporous silica nanoparticles markedly enhanced cytotoxicity in hepatocellular carcinoma cells

ZL Kong, HP Kuo, A Johnson, LC Wu… - International journal of …, 2019 - mdpi.com
Curcumin, a natural polyphenol extracted from a perennial herb Curcuma longa has been
verified for many physiological activities such as anti-oxidant, anti-inflammatory, and anti …

[HTML][HTML] Phytochemicals in cancer and their effect on the PI3K/AKT-mediated cellular signalling

OG Issinger, B Guerra - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Protein kinases belong to the largest family of enzymes controlling every aspect of cellular
activity including gene expression, cell division, differentiation and metabolism. They are …

[HTML][HTML] A comprehensive review on physiological effects of curcumin

R Ahsan, M Arshad, M Khushtar, MA Ahmad… - Drug …, 2020 - thieme-connect.com
Turmeric (Curcuma longa Linn) is an herbal medicine which is traditionally used as a spice,
food colouring or flavouring agent and widely used for several diseases such as biliary …

Enhanced antioxidant and anti-inflammatory effects of self-nano and microemulsifying drug delivery systems containing curcumin

L Józsa, G Vasvári, D Sinka, D Nemes, Z Ujhelyi… - Molecules, 2022 - mdpi.com
Turmeric has been used for decades for its antioxidant and anti-inflammatory effect, which is
due to an active ingredient isolated from the plant, called curcumin. However, the extremely …