• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …

Abstract Aim The “2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic
Disease” provides recommendations to guide clinicians in the diagnosis, genetic evaluation …

The aim of this International Menopause Society White Paper on premature ovarian
insufficiency (POI) is to provide the latest information regarding this distressing condition …

This review provides an updated summary of the state of our knowledge of the genetic
contributions to the pathogenesis of congenital heart disease. Since 2007, when the initial …

Turner syndrome (TS) is a condition in females missing the second sex chromosome (45, X)
or parts thereof. It is considered a rare genetic condition and is associated with a wide range …

Turner syndrome is a rare condition in women that is associated with either complete or
partial loss of one X chromosome, often in mosaic karyotypes. Turner syndrome is …

The term differences of sex development (DSDs; also known as disorders of sex
development) refers to a heterogeneous group of congenital conditions affecting human sex …

not override in any way whatsoever the individual responsibility of health professionals to
make appropriate and accurate decisions in consideration of each patient's health condition …

Abstract The Growth Hormone Research Society (GRS) convened a Workshop in March
2019 to evaluate the diagnosis and therapy of short stature in children. Forty-six …