Antibacterial fluoroquinolones (FQs) are frequently used in treating infections. However, the
value of FQs is debatable due to their association with severe adverse effects (AEs). The …

Highlights•This drug list provides access to the largest number of drugs classified for human
hepatotoxicity.•DILIst (DILI severity and toxicity) is the result of augmentation of five DILI …

Importance Estimates of the incidence of overall antibiotic-associated adverse drug events
(ADEs) in hospitalized patients are generally unavailable. Objective To describe the …

This practical studying involved preparation and development of new medical derivatives of
ciprofloxacin drug via series of chemical reactions to preparation new derivatives to resist …

Abstract Ciprofloxacin (CIP)(human use) and enrofloxacin (ENR)(veterinary use) are
synthetic anti-infectious medications that belong to the second generation of …

Drug-induced liver injury (DILI) is an important differential diagnosis in patients with
abnormal liver tests and normal hepatobiliary imaging. Of all known liver diseases, the …

Introduction: Antiretroviral and anti-tuberculosis (TB) drugs are often co-administered in
people living with HIV (PLWH). Early initiation of antiretroviral therapy (ART) during TB …

Nipah virus (NiV) has been an alarming threat to human populations in southern Asia for
more than a decade. It is one of the most deadly viruses in the Mononegavirales order …

Introduction: Quinolones are widely used antimicrobials with good efficacy and favourable
safety. Recently, forms of quinolone toxicity such as peripheral neuropathy, retinal …

The delayed reporting of antimicrobial susceptibility testing remains a limiting factor in
clinical decision-making in the treatment of bacterial infection. This study evaluates the use …