Cancer cells reprogram their metabolism to meet biosynthetic needs and to adapt to various
microenvironments. Accelerated glycolysis offers proliferative benefits for malignant cells by …

Ovarian cancer is the most lethal gynecologic tumor, with the highest mortality rate.
Numerous studies have been conducted on the treatment of ovarian cancer in the hopes of …

Our previous study revealed that PI3K/AKT/mTOR signaling was associated with SCLC
radioresistance. SBC2 cells were used as primary radioresistance models, while H446 cells …

Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is an important cofactor in
the progress of antioxidant synthesis and biosynthesis, and an abnormal NADPH level has …

Introduction Ovarian cancer (OC) is a gynecological tumor disease, which is usually
diagnosed at an advanced stage and has a poor prognosis. It has been established that the …

Metabolic reprogramming, especially reprogrammed glucose metabolism, is a well-known
cancer hallmark related to various characteristics of tumor cells, including proliferation …

Abnormal glucose metabolism is a highlight of tumor metabolic reprogramming and is
closely related to the development of malignancies. p52-ZER6, a C2H2-type zinc finger …

Maintaining redox homeostasis is an essential feature of cancer cells, and disrupting this
homeostasis to cause oxidative stress and induce cell death is an important strategy in …

Peritoneal cancers present significant clinical challenges with poor prognosis.
Understanding the role of cancer cell metabolism and cancer-promoting metabolites in …

Epithelial ovarian cancer (EOC) has the highest mortality rate among malignant tumors of
the female reproductive system and the lowest survival rate. This poor prognosis is due to …