Cellular agriculture is an emerging branch of biotechnology that aims to address issues
associated with the environmental impact, animal welfare and sustainability challenges of …

Increasing public awareness of foodborne illnesses, factory farming, and the ecological
footprint of the meat industry, has generated the need for animal-free meat alternatives. In …

Volumetric muscle loss (VML) is an irrecoverable injury associated with muscle loss greater
than 20%. Although hydrogel-based 3D engineered muscles and the decellularized …

Macrophages are key contributors to vascularization, but the mechanisms behind their
actions are not understood. Here, we show that diverse macrophage phenotypes have …

3D cell culture methods confer a high degree of clinical and biological relevance to in vitro
models. This is specifically the case with the spheroid culture, where a small aggregate of …

Generating human skeletal muscle models is instrumental for investigating muscle
pathology and therapy. Here, we report the generation of three-dimensional (3D) artificial …

Enabling angiogenesis is critical for the success of tissue repair therapies and the fate of
tissue-engineered constructs. Although many biochemical signaling molecules have been …

Skeletal muscles have a robust capacity to regenerate, but under compromised conditions,
such as severe trauma, the loss of muscle functionality is inevitable. Research carried out in …

Due to the poor mechanical properties of many hydrogel bioinks, conventional 3D extrusion
bioprinting is usually conducted based on the X–Y plane, where the deposited layers are …

Vascularization of large bone grafts is one of the main challenges of bone tissue
engineering (BTE), and has held back the clinical translation of engineered bone constructs …