In this work we model the glomerular filtration barrier, the structure responsible for filtering
the blood and preventing the loss of proteins, using human podocytes and glomerular …

Recent studies indicate that the podocyte compartment is more dynamic than previously
believed. Bidirectional exchange with neighboring cellular compartments provides a …

The human kidney contains approximately one million nephrons. As the functional unit of the
kidney, the nephron affords an opportunity to approximate the kidney at a microphysiological …

Current technologies and available scaffold materials do not support long‐term cell viability,
differentiation, and maintenance of podocytes, the ultra‐specialized kidney resident cells …

Kidney glomerulosclerosis commonly progresses to end-stage kidney failure, but
pathogenic mechanisms are still poorly understood. Here, we show that podocyte …

Podocytes play a critical role in glomerular barrier function, both in health and disease.
However, in vivo terminally differentiated podocytes are difficult to be maintained in in vitro …

The deposition of antipodocyte autoantibodies in the glomerular subepithelial space
induces primary membranous nephropathy (MN), the leading cause of nephrotic syndrome …

Urine represents an unlimited source of patient‐specific kidney cells that can be harvested
noninvasively. Urine derived podocytes and proximal tubule cells have been used to study …

Injection of amniotic fluid stem cells (AFSC) delays the course of progression of renal fibrosis
in animals with Alport Syndrome, enhancing kidney function and improving survival. The …

Podocytes are key cells in the glomerulus, and their damage inevitably leads to proteinuria
and glomerular dysfunction. The more is known about the causes and mechanisms of …