Role of elastic fiber degradation in disease pathogenesis

G Halsey, D Sinha, S Dhital, X Wang… - Biochimica et Biophysica …, 2023 - Elsevier
Elastin is a crucial extracellular matrix protein that provides structural integrity to tissues.
Crosslinked elastin and associated microfibrils, named elastic fiber, contribute to …

[HTML][HTML] Extracellular matrix-derived materials for tissue engineering and regenerative medicine: A journey from isolation to characterization and application

J Noro, H Vilaça-Faria, RL Reis, RP Pirraco - Bioactive Materials, 2024 - Elsevier
Biomaterial choice is an essential step during the development tissue engineering and
regenerative medicine (TERM) applications. The selected biomaterial must present …

Radiofrequency ablation alters the microstructural organization of healthy and enzymatically digested porcine mitral valves

JM Bender, WR Adams, A Mahadevan-Jansen… - Experimental …, 2021 - Springer
Background Myxomatous mitral valve degeneration is a common cause of mitral
regurgitation and is often associated with mitral valve prolapse. With no known targets to …

A method to quantify tensile biaxial properties of mouse aortic valve leaflets

D Chaparro, V Dargam… - Journal of …, 2020 - asmedigitalcollection.asme.org
Understanding aortic valve (AV) mechanics is crucial in elucidating both the mechanisms
that drive the manifestation of valvular diseases as well as the development of treatment …

The effect of the fibrocalcific pathological process on aortic valve stenosis in female patients: a finite element study

M Karnibad, M Sharabi, K Lavon… - Biomedical Physics …, 2022 - iopscience.iop.org
Calcific aortic valve disease (CAVD) is the most common heart valvular disease in the
developed world. Most of the relevant research has been sex-blind, ignoring sex-related …

Introduction to the Special Issue on Advances in Biological Tissue Biomechanics

CH Lee, J Liao - Bioengineering, 2020 - mdpi.com
Advanced experimental and computational biomechanics have become essential
components to better understand the physiological and pathological conditions of biological …

The impact of biological factors, anatomy, and mechanical forces on calcification and fibrosis of cardiac and vascular structures

CB Sylvester, DY Huang, E Jui, KL Singampalli… - Debulking in …, 2022 - Elsevier
The cardiovascular system experiences a unique combination of mechanical forces, which
regulate vascular cell signaling in health and disease. Changes in these mechanical signals …

[HTML][HTML] Die Rolle des Activin A-Systems in der degenerativen Aortenklappenerkrankung bei Diabetes mellitus Typ 2

S Bauer - docserv.uni-duesseldorf.de
Beschreibungen: Die Aortenklappenstenose stellt in Industrieländern das häufigste
Klappenvitium dar. Grund für die Verengung der Aortenklappe ist dabei ein aktiver …

[PDF][PDF] A Method to Quantify Tensile Biaxial Properties of Mouse Aortic Valve Leaflets

I Saytashev, J Bustillo, A Loganathan… - researchgate.net
Understanding aortic valve (AV) mechanics is crucial in elucidating both the mechanisms
that drive the manifestation of valvular diseases as well as the development of treatment …