The amino acid sequence of a protein affects both its structure and its function. Thus, the
ability to modify the sequence, and hence the structure and activity, of individual proteins in …

This chapter reviews and integrates much of what has been learned on the processes of
technological evolution, their main features, and their effects on the evolution of industries …

Importance Hospitals use rates from the best quartile or decile as benchmarks for quality
improvement aims, but to what extent these aims are achievable is uncertain. Objective To …

We develop a tractable model of endogenous production networks. Each one of a number of
products can be produced by combining labor and an endogenous subset of the other …

An important study of the relationship between technology, skills, and economic inequality
that answers some of the most pressing economic questions of our time Today's great …

We propose an empirical framework for assessing the vibrancy and trajectory of regional
entrepreneurial ecosystems. We apply this framework to study the US National Capital …

This article presents an overview of the recent development in the new economic geography
(NEG), and discusses possible directions of its future development. Since several surveys …

Companies innovating in dynamic environments face the combined challenge of
unforeseeable uncertainty (the inability to recognize the relevant influence variables and …

Invention has been commonly conceptualized as a search over a space of combinatorial
possibilities. Despite the existence of a rich literature, spanning a variety of disciplines …

Much work on technological change agrees that the combination of new and existing
technological capabilities is one of the principal sources of inventive novelty, and that there …