Feature detection by retinal ganglion cells

D Kerschensteiner - Annual review of vision science, 2022 - annualreviews.org
Retinal circuits transform the pixel representation of photoreceptors into the feature
representations of ganglion cells, whose axons transmit these representations to the brain …

Unified classification of mouse retinal ganglion cells using function, morphology, and gene expression

J Goetz, ZF Jessen, A Jacobi, A Mani, S Cooler… - Cell reports, 2022 - cell.com
Classification and characterization of neuronal types are critical for understanding their
function and dysfunction. Neuronal classification schemes typically rely on measurements of …

High-density electrode recordings reveal strong and specific connections between retinal ganglion cells and midbrain neurons

J Sibille, C Gehr, JI Benichov… - Nature …, 2022 - nature.com
The superior colliculus is a midbrain structure that plays important roles in visually guided
behaviors in mammals. Neurons in the superior colliculus receive inputs from retinal …

Nanotechnology for vision restoration

G Lanzani, G Chiaravalli, E Colombo… - Nature Reviews …, 2024 - nature.com
Degenerative retinal dystrophies, such as retinitis pigmentosa and age-related macular
degeneration, cause the progressive loss of retinal photoreceptors, which leads to …

Thrombospondin-1 proteomimetic polymers exhibit anti-angiogenic activity in a neovascular age-related macular degeneration mouse model

W Choi, AK Nensel, S Droho, MA Fattah… - Science …, 2023 - science.org
Neovascular age-related macular degeneration (nAMD) is the leading cause of blindness in
the developed world. Current therapy includes monthly intraocular injections of anti-VEGF …

Classical center-surround receptive fields facilitate novel object detection in retinal bipolar cells

JA Gaynes, SA Budoff, MJ Grybko, JB Hunt… - Nature …, 2022 - nature.com
Antagonistic interactions between center and surround receptive field (RF) components lie
at the heart of the computations performed in the visual system. Circularly symmetric center …

Retinal patterns and the cellular repertoire of neuropsin (Opn5) retinal ganglion cells

SP D'Souza, DI Swygart, SR Wienbar… - Journal of …, 2022 - Wiley Online Library
Obtaining a parts list of the sensory components of the retina is vital to understand the effects
of light in behavior, health, and disease. Rods, cones, and intrinsically photosensitive retinal …

Distinct inhibitory pathways control velocity and directional tuning in the mouse retina

MT Summers, MB Feller - Current Biology, 2022 - cell.com
The sensory periphery is responsible for detecting ethologically relevant features of the
external world, using compact, predominantly feedforward circuits. Visual motion is a …

Feedback from retinal ganglion cells to the inner retina

A Vlasiuk, H Asari - PLoS One, 2021 - journals.plos.org
Retinal ganglion cells (RGCs) are thought to be strictly postsynaptic within the retina. They
carry visual signals from the eye to the brain, but do not make chemical synapses onto other …

Generative model of autoencoders self-learning on images represented by count samples

VE Antsiperov - Automation and Remote Control, 2022 - Springer
The paper substantiates the concept of autoencoders focused on automatic generation of
compressed images. We propose a solution to the problem of synthesizing such …