Toxic effects of di‐2‐ethylhexyl phthalate: An overview

SSS Rowdhwal, J Chen - BioMed research international, 2018 - Wiley Online Library
Di‐2‐ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products,
especially medical devices, furniture materials, cosmetics, and personal care products …

[HTML][HTML] Heavy metals, halogenated hydrocarbons, phthalates, glyphosate, cordycepin, alcohol, drugs, and herbs, assessed for liver injury and mechanistic steps

R Teschke, TD Xuan - Frontiers in Bioscience-Landmark, 2022 - imrpress.com
Aluminum, arsenic, cadmium, chromium, cobalt, copper, iron, lead, mercury, nickel, thallium,
titanium, zinc, carbon tetrachloride, phthalates, glyphosate, alcohol, drugs, and herbs are …

DEHP induces ferroptosis in testes via p38α-lipid ROS circulation and destroys the BTB integrity

L Yang, L Jiang, X Sun, J Li, N Wang, X Liu… - Food and Chemical …, 2022 - Elsevier
Abstract Exposure to Di (2-ethylhexyl) phthalate (DEHP) has been associated with toxic
effects of the reproductive system. However, the exact mechanism remains to be elucidated …

DEHP-induced mitophagy and mitochondrial damage in the heart are associated with dysregulated mitochondrial biogenesis

H Zhang, Y Zhao, JG Cui, XN Li, JL Li - Food and Chemical Toxicology, 2022 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a plasticizer widely used in agricultural and
industrial plastic products. Many researchers have demonstrated that DEHP can cause …

Di (2-ethylhexyl) phthalate induced hepatotoxicity in quail (Coturnix japonica) via modulating the mitochondrial unfolded protein response and NRF2 mediated …

Q Zhang, Y Zhao, M Talukder, Y Han, C Zhang… - Science of The Total …, 2019 - Elsevier
Among ubiquitously found environmental contaminants in the ecosystem, di (2-ethylhexyl)
phthalate (DEHP) is an important environmental contaminant used as plasticizer in medical …

Toxic effects of the mixture of phthalates and bisphenol a—subacute oral toxicity study in wistar rats

K Baralić, A Buha Djordjevic, K Živančević… - International journal of …, 2020 - mdpi.com
Phthalates and bisphenol A, classified as endocrine disruptors, have weak estrogenic, anti-
androgenic properties, and affect thyroid hormone regulation. The aim of this study on male …

[PDF][PDF] Role of oxidative stress in male reproductive dysfunctions with reference to phthalate compounds

S Sedha, S Kumar, S Shukla - Urology journal, 2015 - urologyjournal.org
Purpose: A wide variety of environmental chemicals/xenobiotics including phthalates have
been shown to cause oxidative stress targeting the endocrine system and cause …

Concentrations of several phthalates contaminants in Egyptian bottled water: Effects of storage conditions and estimate of human exposure

G Zaki, T Shoeib - Science of the Total Environment, 2018 - Elsevier
The occurrence and concentrations of six common phthalates were investigated for the first
time in bottled water locally produced in the Egyptian market. The compounds investigated …

Di (2-ethylhexyl) phthalate exacerbates non-alcoholic fatty liver in rats and its potential mechanisms

H Chen, W Zhang, B Rui, S Yang, W Xu… - Environmental toxicology …, 2016 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) may be responsible for inducing alterations
similar to those encountered in nonalcoholic fatty liver disease (NAFLD). The aim of the …

The increase of ROS caused by the interference of DEHP with JNK/p38/p53 pathway as the reason for hepatotoxicity

Y Huang, C Wu, Y Ye, J Zeng, J Zhu, Y Li… - International journal of …, 2019 - mdpi.com
As the most commonly used plasticizer, Di-(2-ethylhexyl)-phthalate (DEHP) exists
everywhere in the environment due to the widespread use of polyvinyl chloride (PVC) in …