Palmitoylation, a lipid-based posttranslational protein modification, plays a crucial role in
regulating various aspects of neuronal function through altering protein membrane …

One of the first molecular events in neurodegenerative diseases, regardless of etiology, is
protein mislocalization. Protein mislocalization in neurons is often linked to proteostasis …

Protein lipidation is a common post-translational modification of proteins that plays an
important role in human physiology and pathology. One form of protein lipidation, S …

Mammalian metallothioneins (MTs) are small cysteine-rich proteins whose primary role is
participation in zinc and copper homeostasis. Ever since their discovery, MTs have been …

Neuronal ankyrin-B is an intracellular scaffolding protein that plays multiple roles in the
axon. By contrast, relatively little is known about the function of ankyrin-B in dendrites, where …

S-palmitoylation is a reversible covalent post-translational modification of cysteine thiol side
chain by palmitic acid. S-palmitoylation plays a critical role in a variety of biological …

Many neurological disorders derive from, or can be attributed to the disruptions in neuronal
plasticity. The GABAB receptor (GABA BR) mediates slow inhibitory neurotransmission in …